Biomedical Engineering Reference
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or
m ( T p )
m ( p )
1
|∇ u n T | .
M p =
(11.18)
T N p
The averaging of the gradients (11.17) has been used in [25, 56], and the ap-
proximation (11.18) is new and we have found it very useful regarding good
convergence properties in solving the linear systems (see below) iteratively for
ε 1. Regularizations of both the approximations of the capacity function are
as follows: either
1
|∇ u n 1
M p =
(11.19)
| ε
p
or
m ( T p )
m ( p )
1
|∇ u n T | ε .
M p =
(11.20)
T N p
Now we can define coefficients, where the ε -regularization is taken into account,
namely,
b n 1
p
= M p m ( p ) ,
(11.21)
g T
|∇ u n 1
T
1
h pq
a n 1
c pq
pq =
| ε ,
(11.22)
T E pq
which together with (11.15) and (11.16) give the following.
Fully-discrete semi-implicit co-volume scheme. Let u p , p = 1 ,..., M ,
be given discrete initial values of the segmentation function. Then, for n =
1 ,..., N we look for u p , p = 1 ,..., M, satisfying
b n p u p + τ
a n 1
pq ( u p u q ) = b n p u n 1
(11.23)
.
p
q C p
Theorem. There exists a unique solution ( u 1 ,..., u n M ) of the scheme (11.23)
for any τ> 0 , ε> 0 and for every n = 1 ,..., N. Moreover, for any τ> 0 , ε> 0
the following stability estimate holds
u p min
p
u p max
p
u p max
p
u p ,
min
p
1 n N .
(11.24)
Proof. The system (11.23) can be rewritten in the form
b n 1
p
a n 1
pq
u p τ
a n 1
pq u q = b n p u n 1
(11.25)
+ τ
.
p
q C p
q C p
 
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