Chemistry Reference
In-Depth Information
11
FLUORINATED ARYL NITRENE
PRECURSORS
E
LISA
L
EYVA
,D
ENISSE DE
L
OERA
,S
OCORRO
L
EYVA
,
AND
R
OGELIO
J
IMENEZ
-C
ATA
˜
O
11.1 Introduction
11.2 Photochemistry of Phenyl Azide: A General Mechanism
11.3 Photochemistry of Fluorinated Phenyl Azides in Different Solvents
11.4 Photochemistry of Fluorinated Phenyl Azides in Amines
11.4.1 Reactions in Diethylamine
11.4.2 Reactions in Aniline
11.5 Oxidation of Fluoroanilines
11.6 Novel Fluoro Aryl Nitrene Precursors
11.6.1 Fluorinated 2-Nitrophenyl Azides and 2-Nitroanilines
11.6.2 7-Azido-1-ethyl-6,8-difluoroquinolone-3-carboxylate
11.7 Photoaffinity Labeling and Bifunctional Photochemical Probes
11.8 Conclusions and Outlook
Acknowledgments
References
11.1
INTRODUCTION
Polyfluorinated aryl nitrenes are useful reagents in synthetic organic chemistry,
1
for
the covalent modification of polymer surfaces,
2
and in photoaffinity labeling (PAL).
3
The last technique was invented by Singh, Thornton, and Westheimer in 1962.
4
