Biomedical Engineering Reference
In-Depth Information
1.5 Microencapsulation apparatus (A) and microencapsulation droplet
assembly (B).
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subsequently entrapping the individual beads within a larger sphere of alginate.
Subsequently, the larger sphere is then immersed in PLL and alginate as
described above. Lastly, more technologically advanced encapsulators are now
commercially available that utilize various technologies to produce capsules of
smaller diameter with narrow size distribution. The adoption of automated
machines for microencapsulation results in improved reproducibility in terms of
shape, size and morphology. Droplets for bead formation can be formed using an
assortment of techniques such as emulsification or coacervation, rotating disk
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