Biomedical Engineering Reference
In-Depth Information
A long-term study would be useful to evaluate the biological degradation behavior of the
material utilized in this study. BCP ceramics are well known to be biodegradable due both
to body fluid dissolution and bio resorption cellular activity Nery et al., 1990, Piatelli et al.,
1996). It might indicate that the implants utilized in our studies are progressively resorbed,
but the size of the particle might be big (Handschel et al., 2002) The studies reveal that
Ceraform and xenograft are biocompatible. However, the materials did not promote bone
formation.
5. Conclusion
In conclusion, while some vinyl monomers had cytotoxic effects on tissues, their polymers,
Ceraform and Unilab Surgibone were found to be biocompatible in soft and hard tissues
and they seem only to be beneficial bone filler materials in treatment of the bone defects.
Unilab Surgibone and xenograft could be used as bone filler materials in the treatment of
traumatic and post-traumatic skeletal complications (e.g delayed unions, non-unions),
defects due to bone removal (e.g. bone tumors, congenital diseases) or low bone quality (e.g.
osteoporosis, osteopenia) and in other medical fields.
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