Biomedical Engineering Reference
In-Depth Information
5. Conclusion
To sum up, porous silk fibroin scaffold shows good histocyte attachment and has good
histocompatibility. The Porous silk fibroin scaffold can degradate in vivo, but more study
should be made on the mechanism and degradation products.
6. Acknowledgment
The chapter publication was funded by Shanghai Science and Technology Committee,
1052nm03801.
7. References
Murphy AR, Kaplan DL. Biomedical applications of chemically-modified silk fibroin. J
Mater Chem. 2009 Jun 23;19(36):6443-6450.
Rebecca L. Horan, Kathryn Antle, Adam L. Collette, etc.In vitro degradation of silk fibroin.
Biomaterials,Volume 26, Issue 17, June 2005, Pages 3385-3393
Cao Y, Wang B. Biodegradation of silk biomaterials. Int J Mol Sci. 2009 Mar 31;10(4):1514-24.
Wang Y, Rudym DD, Walsh A,etc. In vivo degradation of three-dimensional silk fibroin
scaffolds. Biomaterials. 2008 Aug-Sep;29(24-25):3415-28.
Lammel AS, Hu X, Park SH, etc. Controlling silk fibroin particle features for drug delivery.
Biomaterials. 2010 Jun;31(16):4583-91.
Wang X, Yucel T, Lu Q, etc. Silk nanospheres and microspheres from silk/pva blend films
for drug delivery.Biomaterials. 2010 Feb;31(6):1025-35.
Lu yan, Chi fang-lu, Zhao Xia, etc. Experimental study on facial nerve regeneration by
porous silk fibroin conduit. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi.
2006, 41(8),603-606.
Yang Y, Ding F, Wu J, Development and evaluation of silk fibroin-based nerve grafts used
for peripheral nerve regeneration. Biomaterials. 2007 Dec;28(36):5526-35.
Tang X, Ding F, Yang Y,etc. Evaluation on in vitro biocompatibility of silk fibroin-based
biomaterials with primarily cultured hippocampal neurons. J Biomed Mater Res A.
2009 Oct;91(1):166-74.
Guan G, Bai L, Zuo B, etc. Promoted dermis healing from full-thickness skin defect by
porous silk fibroin scaffolds (PSFSs).Biomed Mater Eng. 2010;20(5):295-308.
Bosetti M, Boccafoschi F, Calarco A,etc. Behaviour of human mesenchymal stem cells on a
polyelectrolyte-modified HEMA hydrogel for silk-based ligament tissue
engineering. J Biomater Sci Polym Ed. 2008;19(9):1111-23.
Altman GH, Horan RL, Lu HH, et al . Silk matrix for tissue engineered anterior cruciate
ligaments. Biomaterials, 2002, 23(20): 4131-4141.
Meinel L, Fajardo R, Hofmanna S, et al . Silk implants for the healing of critical size bone
defects. Bone, 2005, 37(5): 688-698.
Hofmann S,Hagenmuller H,Koch AM, et al .Control of in vitro tissue-engineered bone-like
structures using human mesenchymal stemcells and porous silk scaffolds.
Biomaterials, 2007, 28(6): 1152-1162.
Zhou J, Cao C, Ma X,etc. Electrospinning of silk fibroin and collagen for vascular tissue
engineering.Int J Biol Macromol. 2010 Nov 1;47(4):514-9.
