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[99] Nakahira K, Haspel JA, Rathinam VA, et al. Autophagy proteins regulate innate immune
responses by inhibiting the release of mitochondrial DNA mediated by the NALP3
inflammasome. Nat Immunol 2011;12(3):222-30.
[100] Franchi L, Amer A, Body-Malapel M, et al. Cytosolic flagellin requires Ipaf for activation
of caspase-1 and interleukin 1beta in Salmonella-infected macrophages. Nat Immunol
2006;7(6):576-82.
[101] Rathinam VA, Jiang Z, Waggoner SN, et al. The AIM2 inflammasome is essential for host
defense against cytosolic bacteria and DNA viruses. Nat Immunol 2010;11(5):395-402.
[102] Hornung V, Ablasser A, Charrel-Dennis M, et al. AIM2 recognizes cytosolic dsDNA and
forms a caspase-1-activating inflammasome with ASC. Nature 2009;458(7237):514-8.
[103] Kimkong I, Avihingsanon Y, Hirankarn N. Expression profile of HIN200 in leukocytes
and renal biopsy of SLE patients by real-time RT-PCR. Lupus 2009;18(12):1066-72.
[104] Penack O, Smith OM, Cunningham-Bussel A, et al. NOD2 regulates hematopoietic cell
function during graft-versus-host disease. J Exp Med 2009;206(10):2101-10.
[105] Holler E, Rogler G, Brenmoehl J, et al. Prognostic significance of NOD2/CARD15
variants in HLA-identical sibling hematopoietic stem cell transplantation: effect on
long-term outcome is confirmed in 2 independent cohorts and may be modulated by
the type of gastrointestinal decontamination. Blood 2006;107(10):4189-93.
[106] Holler E, Rogler G, Herfarth H, et al. Both donor and recipient NOD2/CARD15
mutations associate with transplant-related mortality and GvHD following allogeneic
stem cell transplantation. Blood 2004;104(3):889-94.
[107] van der Velden WJ, Blijlevens NM, Maas FM, et al. NOD2 polymorphisms predict severe
acute graft-versus-host and treatment-related mortality in T-cell-depleted haematopoi-
etic stem cell transplantation. Bone Marrow Transplant 2009;44(4):243-8.
[108] Elmaagacli AH, Koldehoff M, Hindahl H, et al. Mutations in innate immune system
NOD2/CARD 15 and TLR-4 (Thr399Ile) genes influence the risk for severe acute
graft-versus-host disease in patients who underwent an allogeneic transplantation.
Transplantation 2006;81(2):247-54.
[109] Granell M, Urbano-Ispizua A, Arostegui JI, et al. Effect of NOD2/CARD15 variants in T-
cell depleted allogeneic stem cell transplantation. Haematologica 2006;91(10):1372-6.
[110] Sairafi D, Uzunel M, Remberger M, Ringden O, Mattsson J. No impact of NOD2/
CARD15 on outcome after SCT. Bone Marrow Transplant 2008;41(11):961-4.
[111] Gruhn B, Intek J, Pfaffendorf N, et al. Polymorphism of interleukin-23 receptor
gene but not of NOD2/CARD15 is associated with graft-versus-host disease after
hematopoietic stem cell transplantation in children. Biol Blood Marrow Transplant
2009;15(12):1571-7.
[112] Mayor NP, Shaw BE, Hughes DA, et al. Single nucleotide polymorphisms in the NOD2/
CARD15 gene are associated with an increased risk of relapse and death for patients
with acute leukemia after hematopoietic stem-cell transplantation with unrelated
donors. J Clin Oncol 2007;25(27):4262-9.
[113] Dickinson AM, Holler E. Polymorphisms of cytokine and innate immunity genes and
GVHD. Best Pract Res Clin Haematol 2008;21(2):149-64.
[114] Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome
activation. Nature 2011;469(7329):221-5.
[115] Fox CJ, Hammerman PS, Thompson CB. Fuel feeds function: energy metabolism and
the T-cell response. Nat Rev Immunol 2005;5(11):844-52.
[116] O'Neill LA. A critical role for citrate metabolism in LPS signalling. Biochem J
2011;438(3):e5-6.
[117] Houtkooper RH, Pirinen E, Auwerx J. Sirtuins as regulators of metabolism and
healthspan. Nat Rev Mol Cell Biol 2012;13(4):225-38.
[118] Stienstra R, Joosten LA, Koenen T, et al. The inflammasome-mediated caspase-1
activation controls adipocyte differentiation and insulin sensitivity. Cell Metab
2010;12(6):593-605.
[119] Wen H, Gris D, Lei Y, et al. Fatty acid-induced NLRP3-ASC inflammasome activation
interferes with insulin signaling. Nat Immunol 2011;12(5):408-15.
[120] Vandanmagsar B, Youm YH, Ravussin A, et al. The NLRP3 inflammasome instigates
obesity-induced inflammation and insulin resistance. Nat Med 2011;17(2):179-88.
[121] Schroder K, Zhou R, Tschopp J. The NLRP3 inflammasome: a sensor for metabolic
danger? Science 2010;327(5963):296-300.
[122] Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links
oxidative stress to inflammasome activation. Nat Immunol 2010;11(2):136-40.
[123] Ferrer IR, Araki K, Ford ML. Paradoxical aspects of rapamycin immunobiology in
transplantation. Am J Transplant 2011;11(4):654-9.
[124] Powell JD, Delgoffe GM. The mammalian target of rapamycin: linking T cell differentia-
tion, function, and metabolism. Immunity 2010;33(3):301-11.
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