Biology Reference
In-Depth Information
[162] Hill GR, Olver SD, Kuns RD, Varelias A, Raffelt NC, Don AL, et al. Stem cell mobiliza-
tion with G-CSF induces type 17 differentiation and promotes scleroderma. Blood
2010;116(5):819-28.
[163] Das R, Chen X, Komorowski R, Hessner MJ, Drobyski WR. Interleukin-23 secretion by
donor antigen-presenting cells is critical for organ-specific pathology in graft-versus-
host disease. Blood 2009;113(10):2352-62.
[164] Das R, Komorowski R, Hessner MJ, Subramanian H, Huettner CS, Cua D, et al.
Blockade of interleukin-23 signaling results in targeted protection of the colon and
allows for separation of graft-versus-host and graft-versus-leukemia responses. Blood
2010;115(25):5249-58.
[165] Dander E, Balduzzi A, Zappa G, Lucchini G, Perseghin P, Andre V, et al. Interleukin-
17-producing T-helper cells as new potential player mediating graft-versus-host
disease in patients undergoing allogeneic stem-cell transplantation. Transplantation
2009;88(11):1261-72.
[166] Broady R, Yu J, Chow V, Tantiworawit A, Kang C, Berg K, et al. Cutaneous GVHD is
associated with the expansion of tissue-localized Th1 and not Th17 cells. Blood
2010;116(25):5748-51.
[167] Ratajczak P, Janin A, Peffault de Latour R, Leboeuf C, Desveaux A, Keyvanfar K, et al.
Th17/Treg ratio in human graft-versus-host disease. Blood 2010;116(7):1165-71.
[168] Espinoza JL, Takami A, Nakata K, Onizuka M, Kawase T, Akiyama H, et al. A genetic
variant in the IL-17 promoter is functionally associated with acute graft-versus-host
disease after unrelated bone marrow transplantation. PLoS One 2011;6(10):e26229.
[169] Elmaagacli AH, Koldehoff M, Landt O, Beelen DW. Relation of an interleukin-23 recep-
tor gene polymorphism to graft-versus-host disease after hematopoietic-cell transplan-
tation. Bone Marrow Transplant 2008;41(9):821-6.
[170] Gruhn B, Intek J, Pfaffendorf N, Zell R, Corbacioglu S, Zintl F, et al. Polymorphism of
interleukin-23 receptor gene but not of NOD2/CARD15 is associated with graft-versus-
host disease after hematopoietic stem cell transplantation in children. Biol Blood Mar-
row Transplant 2009;15(12):1571-7.
[171] Nguyen Y, Al-Lehibi A, Gorbe E, Li E, Haagenson M, Wang T, et al. Insufficient evidence
for association of NOD2/CARD15 or other inflammatory bowel disease-associated
markers on GVHD incidence or other adverse outcomes in T-replete, unrelated donor
transplantation. Blood 2010;115(17):3625-31.
[172] Spolski R, Leonard WJ. Interleukin-21: basic biology and implications for cancer and
autoimmunity. Annu Rev Immunol 2008;26:57-79.
[173] Habib T, Senadheera S, Weinberg K, Kaushansky K. The common gamma chain
(gamma c) is a required signaling component of the IL-21 receptor and supports IL-21-
induced cell proliferation via JAK3. Biochemistry 2002;41(27):8725-31.
[174] Asao H, Okuyama C, Kumaki S, Ishii N, Tsuchiya S, Foster D, et al. Cutting edge: the
common gamma-chain is an indispensable subunit of the IL-21 receptor complex. J
Immunol 2001;167(1):1-5.
[175] Parrish-Novak J, Dillon SR, Nelson A, Hammond A, Sprecher C, Gross JA, et al. Interleu-
kin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte
function. Nature 2000;408(6808):57-63.
[176] Ozaki K, Kikly K, Michalovich D, Young PR, Leonard WJ. Cloning of a type I cyto-
kine receptor most related to the IL-2 receptor beta chain. Proc Natl Acad Sci U S A
2000;97(21):11439-44.
[177] Hanash AM, Kappel LW, Yim NL, Nejat RA, Goldberg GL, Smith OM, et al. Abrogation
of donor T-cell IL-21 signaling leads to tissue-specific modulation of immunity and
separation of GVHD from GVL. Blood 2011;118(2):446-55.
[178] Meguro A, Ozaki K, Hatanaka K, Oh I, Sudo K, Ohmori T, et al. Lack of IL-21 signal
attenuates graft-versus-leukemia effect in the absence of CD8 T-cells. Bone Marrow
Transplant 2011;46(12):1557-65.
[179] Hippen KL, Bucher C, Schirm DK, Bearl AM, Brender T, Mink KA, et al. Blocking IL-21
signaling ameliorates xenogeneic GVHD induced by human lymphocytes. Blood
2012;119(2):619-28.
[180] Bucher C, Koch L, Vogtenhuber C, Goren E, Munger M, Panoskaltsis-Mortari A, et al.
IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T
regulatory cell generation. Blood 2009;114(26):5375-84.
[181] Waskow C, Liu K, Darrasse-Jeze G, Guermonprez P, Ginhoux F, Merad M, et al. The
receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral
lymphoid tissues. Nat Immunol 2008;9(6):676-83.
[182] Liu K, Nussenzweig MC. Origin and development of dendritic cells. Immunol Rev
2010;234(1):45-54.
[183] Bogunovic M, Ginhoux F, Helft J, Shang L, Hashimoto D, Greter M, et al. Origin of the
lamina propria dendritic cell network. Immunity 2009;31(3):513-25.
389
Search WWH ::
Custom Search