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[4] Yao Z, Fanslow WC, Seldin MF, Rousseau AM, Painter SL, Comeau MR, et al. Herpes-
virus saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor.
Immunity 1995;3:811-21.
[5] Fossiez F, Djossou O, Chomarat P, Flores-Romo L, Ait-Yahia S, Maat C, et al. T cell
interleukin 17 induces stromal cells to produce proinflammatory and hematopoietic
cytokines. J Exp Med 1996;183:2593-603.
[6] Jovanovic DV, DiBattista JA, Martel-Pelletier J, Jolicoeur FC, He Y, Zhang M, et al. IL-17
stimulates the production and expression of proinflammatory cytokines, IL-1 beta and
TNF-alpha by human macrophages. J Immunol 1998;160:3513-21.
[7] Glimcher LH, Murphy KM. Lineage commitment in the immune system: the T helper
lymphocyte grows up. Genes Dev 2000;14:1693-711.
[8] Oppmann B, Lesley R, Blom B, Timans JC, Xu Y, Hunte B, et al. Novel p19 protein
engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as
distinct from IL-12. Immunity 2000;13:715-25.
[9] Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, et al. Interleukin-23 rather
than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.
Nature 2003;421:744-8.
[10] Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a
distinct CD4 + T cell activation state characterized by the production of interleukin-17.
J Biol Chem 2003;278:1910-4.
[11] Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, et al. IL-23 is es-
sential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin
Invest 2006;116:1310-6.
[12] Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, et al. IL-23
drives a pathogenic T cell population that induces autoimmune inflammation. J Exp
Med 2005;201:233-40.
[13] Murphy CA, Langrish CL, Chen Y, Blumenschein W, McClanahan T, Kastelein RA, et al.
Divergent pro- and anti inflammatory roles for IL-23 and IL-12 in joint autoimmune
inflammation. J Exp Med 2003;198:1951-7.
[14] Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley CE, Lafaille JJ, et al. The orphan
nuclear receptor ROR-gammat directs the differentiation program of proinflammatory
IL-17 + T helper cells. Cell 2006;126:1121-33.
[15] Szabo SJ, Kim ST, Costa GL, Zhang X, Fathman CG, Glimcher LH. A novel transcription
factor, T-bet, directs T H 1 lineage commitment. Cell 2000;100:655-69.
[16] Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for T H 2
cytokine gene expression in CD4 T cells. Cell 1997;89:587-96.
[17] Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, et al.
Interleukin 17-producing CD4 + effector T cells develop via a lineage distinct from the T
helper type 1 and 2 lineages. Nat Immunol 2005;6:1123-32.
[18] Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, et al. A distinct lineage of CD4
T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol
2005;6:1133-41.
[19] Hoeve MA, Savage ND, de Boer T, Langenberg DM, de Waal Malefyt R, Ottenhoff TH,
et al. Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells.
Eur J Immunol 2006;36:661-70.
[20] Mangan PR, Harrington LE, O'Quinn DB, Helms WS, Bullard DC, Elson CO, et al.
Transforming growth factor-beta induces development of the T(H)17 lineage. Nature
2006;441:231-4.
[21] McGeachey MJ, Chen Y, Tato CM, Laurence A, Joyce-Shaikh B, Blumenschein WM, et al.
The interleukin 23 receptor is essential for the terminal differentiation of interleukin
17-producing effector T helper cells in vivo. Nat Immunol 2009;10:314-24.
[22] Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context
of an inflammatory cytokine milieu supports de novo differentiation of IL-17-produc-
ing T cells. Immunity 2006;24:179-89.
[23] Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, et al. Reciprocal developmental
pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature
2006;441:235-8.
[24] Zhou L, Lopes JE, Chong MM, Ivanov II, Min R, Victora GD, et al. TGF-beta-induced
Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function. Na-
ture 2008;453:236-40.
[25] Chen Z, Laurence A, Kanno Y, Pacher-Zavisin M, Zhu BM, Tato C, et al. Selective regula-
tory function of Socs3 in the formation of IL-17-secreting T cells. Proc Natl Acad Sci
USA 2006;103:8137-42.
[26] Liu X, Lee YS, Yu CR, Egwuagu CE. Loss of STAT3 in CD4+ T cells prevents development
of experimental autoimmune diseases. J Immunol 2008;180:6070-6.
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