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[10] Koch MA, Tucker-Heard G, Perdue NR, Killebrew JR, Urdahl KB, Campbell DJ. The tran-
scription factor T-bet controls regulatory T cell homeostasis and function during type 1
inflammation. Nat Immunol 2009;10(6):595-602.
[11] Yang XO, Nurieva R, Martinez GJ, et al. Molecular antagonism and plasticity of regula-
tory and inflammatory T cell programs. Immunity 2008;29(1):44-56.
[12] Hegazy AN, Peine M, Helmstetter C, et al. Interferons direct Th2 cell reprogramming to
generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell func-
tions. Immunity 2010;32(1):116-28.
[13] Amarnath S, Mangus CW, Wang JC, et al. The PDL1-PD1 axis converts human TH1 cells
into regulatory T cells. Sci Transl Med 2011;3(111); 111ra20.
[14] Wang J, Fathman JW, Lugo-Villarino G, et al. Transcription factor T-bet regulates inflam-
matory arthritis through its function in dendritic cells. J Clin Invest 2006;116(2):414-21.
[15] Sullivan BM, Juedes A, Szabo SJ, von Herrath M, Glimcher LH. Antigen-driven effector
CD8 T cell function regulated by T-bet. Proc Natl Acad Sci U S A 2003;100(26):15818-23.
[16] Peng SL, Szabo SJ, Glimcher LH. T-bet regulates IgG class switching and pathogenic
autoantibody production. Proc Natl Acad Sci U S A 2002;99(8):5545-50.
[17] Townsend MJ, Weinmann AS, Matsuda JL, et al. T-bet regulates the terminal maturation
and homeostasis of NK and Valpha14i NKT cells. Immunity 2004;20(4):477-94.
[18] Lord GM, Rao RM, Choe H, et al. T-bet is required for optimal proinflammatory CD4+
T-cell trafficking. Blood 2005;106(10):3432-9.
[19] Frisullo G, Nociti V, Iorio R, et al. Glucocorticoid treatment reduces T-bet and pSTAT1
expression in mononuclear cells from relapsing remitting multiple sclerosis patients.
Clin Immunol 2007;124(3):284-93.
[20] Rao RR, Li Q, Odunsi K, Shrikant PA. The mTOR kinase determines effector versus
memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and
eomesodermin. Immunity 2010;32(1):67-78.
[21] Lighvani AA, Frucht DM, Jankovic D, et al. T-bet is rapidly induced by interferon-gam-
ma in lymphoid and myeloid cells. Proc Natl Acad Sci U S A 2001;98(26):15137-42.
[22] Mullen AC, High FA, Hutchins AS, et al. Role of T-bet in commitment of TH1 cells before
IL-12-dependent selection. Science 2001;292(5523):1907-10.
[23] Sullivan BM, Jobe O, Lazarevic V, et al. Increased susceptibility of mice lacking T-bet
to infection with Mycobacterium tuberculosis correlates with increased IL-10 and
decreased IFN-gamma production. J Immunol 2005;175(7):4593-602.
[24] Neurath MF, Weigmann B, Finotto S, et al. The transcription factor T-bet regulates
mucosal T cell activation in experimental colitis and Crohn's disease. J Exp Med
2002;195(9):1129-43.
[25] Djuretic IM, Levanon D, Negreanu V, Groner Y, Rao A, Ansel KM. Transcription factors
T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. Nat
Immunol 2007;8(2):145-53.
[26] Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by
kinase-mediated interaction of T-bet with GATA-3. Science 2005;307(5708):430-3.
[27] Lazarevic V, Chen X, Shim JH, et al. T-bet represses T(H)17 differentiation by prevent-
ing Runx1-mediated activation of the gene encoding RORgammat. Nat Immunol
2011;12(1):96-104.
[28] Pearce EL, Mullen AC, Martins GA, et al. Control of effector CD8+ T cell function by the
transcription factor eomesodermin. Science 2003;302(5647):1041-3.
[29] Steiner DF, Thomas MF, Hu JK, et al. MicroRNA-29 regulates T-box transcription factors
and interferon-gamma production in helper T cells. Immunity 2011;35(2):169-81.
[30] Intlekofer AM, Takemoto N, Wherry EJ, et al. Effector and memory CD8+ T cell fate
coupled by T-bet and eomesodermin. Nat Immunol 2005;6(12):1236-44.
[31] Sun J, Dodd H, Moser EK, Sharma R, Braciale TJ. CD4+ T cell help and innate-derived
IL-27 induce Blimp-1-dependent IL-10 production by antiviral CTLs. Nat Immunol
2011;12(4):327-34.
[32] Wang L, Wildt KF, Zhu J, et al. Distinct functions for the transcription factors GATA-
3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat Immunol
2008;9(10):1122-30.
[33] Wang Y, Su MA, Wan YY. An essential role of the transcription factor GATA-3 for the
function of regulatory T cells. Immunity 2011;35(3):337-48.
[34] Kurata H, Lee HJ, O'Garra A, Arai N. Ectopic expression of activated Stat6 induces the
expression of Th2-specific cytokines and transcription factors in developing Th1 cells.
Immunity 1999;11(6):677-88.
[35] Yamane H, Zhu J, Paul WE. Independent roles for IL-2 and GATA-3 in stimulating
naive CD4+ T cells to generate a Th2-inducing cytokine environment. J Exp Med
2005;202(6):793-804.
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