Biology Reference
In-Depth Information
Kimble SR (2006) Interaction between the AMP-activated protein kinase and mTOR signaling
pathways. Med Sci Sports Exercise 38:1958-1964
Knudson AG (1988) The genetics of childhood cancer. Bull Cancer 73:135-138
Kudchodkar SB, Yu Y, Maguire T, Alwine JC (2004) Human cytomegalovirus infection induces
rapamycin insensitive phosphorylation of downstream effectors of mTOR kinase. J Virol
78:11030-11039
Kudchodkar SB, Yu Y, Maguire TG, Alwine JC (2006) Human cytomegalovirus infection alters
the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing
complexes. Proc Natl Acad Sci U S A 103:14182-14187
Kudchodkar SB, Del Prete GQ, Maguire TG, Alwine JC (2007) AMPK-mediated inhibition
of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus
infection. J Virol 81:3649-3651
Long X, Lin Y, Ortiz-Vega S, Yonezawa K, Avruch J (2005a) Rheb binds and regulates the mTOR
kinase. Curr Biol 15:702-713
Long X, Ortiz-Vega S, Lin Y, Avruch J (2005b) Rheb binding to mammalian target of rapamycin
(mTOR) is regulated by amino acid sufficiency. J Biol Chem 280:23433-23436
Luo Z, Saha AK, Xiang X, Ruderman NB (2005) AMPK, the metabolic syndrome and cancer.
Trends Pharmacol Sci 26:69-76
Mamane Y, Petroulakis E, LeBacquer O, Sonenberg N (2006) mTOR, translation initiation and
cancer. Oncogene 25:6416-6422
Mohr I (2006) Phosphorylation and dephosphorylation events that regulate viral mRNA translation.
Virus Res 119:89-99
Mumby M (2007) The 3D structure of protein phosphatase 2A: new insights into a ubiquitous
regulator of cell signaling. ACS Chem Biol 2:99-103
Plas DR, Thompson CB (2005) Akt-dependent transformation: there is more to growth than just
surviving. Oncogene 24:7435-7442
Polak P, Hall MN (2006) mTORC2 Caught in a SINful Akt. Dev Cell 11:433-434
Reiling JH, Sabatini DM (2006) Stress and mTORture signaling. Oncogene 25:6373-6383
Sabatini DM, Erdjument-Bromage H, Lui M, Tempst P, Snyder SH (1994) RAFT1: a mammalian
protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast
TORs. Cell 78:35-43
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P,
Sabatini DM (2004) Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive
and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 14:1296-1302
Sarbassov DD, Ali SM, Sabatini DM (2005a) Growing roles for the mTOR pathway. Curr Opin
Cell Biol 17:596-603
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM (2005b) Phosphorylation and regulation of
Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101
Schwarzer R, Tondera D, Arnold W, Giese K, Klippel A, Kaufmann J (2005) REDD1 integrates
hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. Oncogene
24:1138-1149
Sharon-Friling R, Goodhouse J, Colberg-Poley AM, Shenk T (2006) Human cytomegalovirus
pUL37×1 induces the release of endoplasmic reticulum calcium stores. Proc Natl Acad Sci U
S A 130:19117-19122
Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kosmatka M, DePinho RA, Cantley LC (2004) The
LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell 6:91-99
Shen YH, Zhang L, Utama B, Wang J, Gan Y, Wang X, Wang J, Chen L, Vercellotti GM, Coselli
JS, Mehta JL, Wang XL (2006) Human cytomegalovirus inhibits Akt-mediated eNOS activa-
tion through upregulating PTEN (phosphatase and tensin homolog deleted on chromosome
10). Cardiovasc Res 69:502-511
Summers SA, Garza LA, Zhou H, Birnbaum MJ (1998) Regulation of insulin-stimulated glucose
transporter GLUT4 translocation and Akt kinase activity by ceramide. Mol Cell Biol
18:5457-5464
Ueki K, Yamamoto-Honda R, Kaburagi Y, Yamauchi T, Tobe K, Burgering BM, Coffer PJ,
Komuro I, Akanuma Y, Yazaki Y, Kadowaki T (1998) Potential role of protein kinase B in
