Chemokines and Chemokine Receptors Encoded by Cytomegaloviruses - Human Cytomegalovirus - page 226

Table 3 (continued)
Receptor Ligand(s) Ca 2+ mobilization PLC/InsP AC/cAMP/CRE NF- κ B Other signaling effects

HHV- 7 ELC, SLC, By ELC, SLC, Unknown Unknown Unknown Broadens ligand

U12 TARC, MDC TARC & MDC specificity for

(Tadagaki (Tadagaki CCR4 and CCR7

et al. 2005) et al. 2005) (Tadagaki et al. 2007)

HCMV Unknown Unknown Unknown Unknown Unknown

UL78
MCMV Unknown Unknown Unknown Unknown Unknown

M78
RCMV Unknown Unknown Unknown Unknown Unknown

R78
HHV-6 RANTES, By RANTES, Constitutively up via Constitutively down via Unknown Downregulates

U51 eotaxin,MCP- not by MCP-1 Gq/11, more up by G q/11 , up by RANTES, RANTES transcription

1-3, and or eotaxin RANTES stimulation, MCP-1 and eotaxin (Milne et al. 2000)

- 4, KSHV (Fitzsimons not by MCP-1 or via Gi/o (Fitzsimons

vMIP-II et al. 2006) eotaxin (Fitzsimons et al. 2006)

(Milne et al. et al. 2006)

2000;
Fitzsimons
et al. 2006)
HHV-7 ELC, SLC, By ELC, SLC, Unknown Unknown Unknown Alters ligand specificity

U51 TARC, TARC & MDC for CCR4 and

MDC (Tadagaki CCR7 (Tadagaki

(Tadagaki et al. 2005) et al. 2007)

et al. 2005)
HCMV Unknown Unknown Unaffected Unaffected Unaffected

US27 (Waldhoer (Waldhoer (Waldhoer

et al. 2002) et al. 2002) et al. 2002)

HCMV RANTES, Via G ai and G a16 Constitutively up via Constitutively up Constitutively up Various, see text

US28 (Billstrom et al. MCP-1, G q/11 (Casarosa et al. (Waldhoer et al. (Casarosa et al.