Biology Reference
In-Depth Information
Fig. 1
a
HCMV infected HFF (3 h p.i.).
Small green dots
represent pp71 antibodies bound to
viral particles.
Larger green dots
in the (
blue
) nucleus represent pp71 antibodies bound to Daxx,
which is associated with PML at ND10. The three
red domains
located beside the pp71 stained
ND10 denote the localization of IE2 aggregates.
b
Same as
a
, but stained with anti-PML antibodies
in
red
indicating ND10 and by in situ hybridization with HCMV DNA labeling viral genomes
(
green
).
Arrows
point to viral genomes juxtaposed to ND10. The
blue line
was introduced to show
the approximate boundary of the nucleus.
c
Same as
a
, but triple-labeled for the major immediate