NANOTECHNOLOGY AND 3D BIOPRINTING FOR NEURAL TISSUE REGENERATION - 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine - page 305

FIGURE 14.3
Schematic illustration of genetically engineered M13 phage and cell response characterization on aligned self-
assembling nanofibrous matrices (pVIII, pIII and pIX represent proteins). Image is adopted from Merzlyak et al.
(2009) .
For instance, neurogenic peptides can be easily conjugated onto RNTs with controlled spatial dis-
tribution and density in order to improve specific protein adsorption as well as cell function during
neural regeneration.
FIGURE 14.4
Schematic illustration of the self-assembly process of RNTs. (A) Six twin G^C motifs with a RGDSK peptide are
self-assembled into rosette-like supermacrocycles and then stack up into stable helical nanotubes. RNTs with a 11 Å
hollow core are 3-4 nm in diameter and up to several m m long. (B) Atomic force microscopy image of the RNTs
with RGDSK.