Biomedical Engineering Reference
In-Depth Information
Fig. 11.7
Rapid mould with original models (
scaffolds
), obtained by additive manufacturing, and
silicone casting process. Silicone degasifi cation process for enhancing the detail level and avoiding
fi nal porous moulds
process and manufacture of master models were already described in Sect.
10.5
(Figs.
10.13
and
10.14
)
. Even though it is just a one-part mould, the incorporation
of different cavities is aimed at a more productive casting process.
The fi ve circular cavities include different scaffold with different fractal dimen-
sion (2 planar; 2,2; 2,4; 2,6; and 2,8) for assessing the effects of fractal dimension
on cell growth, differentiation and fi nal tissue formation. The rectangular cavity
includes a part with different fractal paths for studying cell crawl and assessing the
impact of fractal dimension on their behaviour.
Figure
11.10
shows fi nal prototypes obtained through beeswax casting using the
mould from Fig.
11.8
. The wax is heated until melting (just above 64 °C) and then
poured into the mould. It is important to preheat the mould at around 70 °C in oven,
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