In Vivo Gene Silencing by Virally Delivered MicroRNA - Viral Vector Approaches in Neurobiology and Brain Diseases - page 257

61. Hommel JD, Sears RM, Georgescu D et al
(2003) Local gene knockdown in the brain
using viral-mediated RNA interference. Nat
Med 9:1539-1544
62. Grimm D, Streetz KL, Jopling CL et al (2006)
Fatality in mice due to oversaturation of cellu-
lar microRNA/short hairpin RNA pathways.
Nature 441:537-541
63. Beer S, Bellovin DI, Lee JS et al (2010) Low-
level shRNA cytotoxicity can contribute to
MYC-induced hepatocellular carcinoma in
adult mice. Mol Ther 18:161-170
64. Bagga S, Bracht J, Hunter S et al (2005)
Regulation by let-7 and lin-4 miRNAs results in
target mRNA degradation. Cell 122:553-563
65. Lim LP, Lau NC, Garrett-Engele P et al
(2005) Microarray analysis shows that some
microRNAs downregulate large numbers of-
target mRNAs. Nature 433:769-773
66. Giraldez AJ, Mishima Y, Rihel J et al (2006)
Zebrafi sh MiR-430 promotes deadenylation
and clearance of maternal mRNAs. Science
312:75-79
67. (2010) BLOCK-iT™ Pol II miR RNAi
Expression Vector Kits. Gateway ® -adapted

expression vector for the expression of
microRNA (miRNA) in mammalian cells under
control of Pol II promoters, User Manual
68. Ahmed MR, Berthet A, Bychkov E et al (2010)
Lentiviral overexpression of GRK6 alleviates
L-dopa-induced dyskinesia in experimental
Parkinson's disease. Sci Transl Med 2:28ra28
69. Gurevich EV, Tesmer JJ, Mushegian A et al
(2012) G protein-coupled receptor kinases:
more than just kinases and not only for GPCRs.
Pharmacol Ther 133:40-69
70. Anderson GR, Cao Y, Davidson S et al (2010)
R7BP complexes with RGS9-2 and RGS7 in
the striatum differentially control motor learn-
ing and locomotor responses to cocaine.
Neuropsychopharmacology 35:1040-1050
71. Tiscornia G, Singer O, Verma IM (2006)
Production and purifi cation of lentiviral vec-
tors. Nat Protoc 1:241-245
72. Ahmed MR, Bychkov E, Gurevich VV et al
(2007) Altered expression and subcellular
distribution of GRK subtypes in the dopamine-
depleted rat basal ganglia is not normalized
by l-DOPA treatment. J Neurochem 104:
1622-1636