Biology Reference
In-Depth Information
chromosome gene expression system using
herpes simplex virus type 1 vectors. EMBO
Rep 7:911-918
211. Olschowka JA, Bowers WJ, Hurley SD,
Mastrangelo MA, Federoff HJ (2003)
Helper-free HSV-1 amplicons elicit a mark-
edly less robust innate immune response in
the CNS. Mol Ther 7:218-227
212. Suzuki M, Kasai K, Saeki Y (2006) Plasmid
DNA sequences present in conventional her-
pes simplex virus amplicon vectors cause rapid
transgene silencing by forming inactive chro-
matin. J Virol 80:3293-3300
213. Suzuki M, Chiocca EA, Saeki Y (2007) Early
STAT1 activation after systemic delivery of
HSV amplicon vectors suppresses transcrip-
tion of the vector-encoded transgene. Mol
Ther 15:2017-2026
214. Suzuki M, Chiocca EA, Saeki Y (2008) Stable
transgene expression from HSV amplicon
vectors in the brain: potential involvement
of immunoregulatory signals. Mol Ther 16:
1727-1736
215. Tsitoura E, Thomas J, Cuchet D, Thoinet K,
Mavromara P, Epstein AL (2009) Infection
with herpes simplex type 1-based amplicon
vectors results in an IRF3/7-dependent, TRL-
independent activation of the innate antiviral
response in primary human fi broblasts. J Gen
Virol 90:2209-2220
Search WWH ::




Custom Search