Computational Fluid and Particle Dynamics (CFPD): An Introduction - Computational Fluid and Particle Dynamics in the Human Respiratory System - page 18

provide CFPD as a practical tool in modern engineering applications. One major
advantage of significance to the medical and pharmaceutical industries is the ability
to simulate fluid-particle flows that are difficult to reproduce experimentally. For
example clinical testing of human respiration of gases and particles is quite invasive
and can be detrimental to a person's health and indeed a CFPD approach can pro-
vide a simpler alternative. A large number of examples have been presented which
demonstrate the use of computational fluid and particle dynamics as an educational
and research tool in many biomedical applications such as human respiration, drug
delivery, and assistance to surgical procedures.
The use of CFPD in biomedical applications is indeed multi-disciplinary, in-
corporating the fundamentals of CFD (computational science, mathematics, fluid
dynamics) with particle science and human anatomy and physiology. This leads to
the question as to whether we actually require the expertise of five specific people—
one from each discipline—to come together for the development of a biomedical
simulation. The answer is obviously not. More likely, this field will require a per-
son to obtain some knowledge subsets from each discipline. Therefore, this topic
is written to equip the reader with the necessary background material for an under-
standing of both the internal workings of a CFD code and its successful operation
and its application to the human respiratory system. In the next chapter, we begin
by presenting the anatomy and physiology of the human respiratory system which
serves as a base for developing the CFPD simulation settings. The primary aim is to
summarise the important features of respiration and how it will be incorporated into
the final computational model.

1.5 Review Questions

1. How does CFPD differ from CFD?
2. What four disciplines does CFPD derive from?
3. What are some of the advantages of using CFPD?
4. What are the limitations and disadvantages of using CFPD?
5. How can CFPD be used as a training tool in medicine?
6. How can CFPD be used for evaluating the toxicology of inhaled particles?
7. What advantages does CFPD hold over experiments, in obtaining these results?
8. What are some applications of CFPD in the biomedical field?