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65
(a)
60
55
50
45
40
35
0.05
0.1
0.15
0.2
0.25
0.3
0.35
0.4
0.45
0.5
0.55
φ
w
65
(b)
60
55
50
DOPE:DOG ratio
1.00:0
8.65:1
45
5.77:1
40
4.82:1
2.87:1
35
0.05
0.1
0.15
0.2
0.25
0.3
φ
w
Figure 3.2
Experimental dependence of
d
hex
on the water volume fraction, ϕ
w
at dif-
ferent dioleoyl phosphatidylethanolamine : dioleoyl glycerol (DOPE : DOG) ratios:
(a) the horizontal lines describe the dependence at fully hydrated lipid heads and (b)
the same dependence at less than full hydration. [Data source: Leikin et al. (1996).]
of the polar lipid heads (it can be estimated on the basis of the structure of
the lipid head). Table 3.2 contains a measured data set for
α
H
I
*
in
1 - palmitoyl - 2 - oleoyl - sn - phopshatidylethandolamine/1 - palmitoyl - 2 - oleoyl -
sn-phopshatidylcholine (POPE/POPC) mixtures. Unfortunately,
α
and
α
H
I
*
is not
connected to an appropriate theoretical model—it is a product of
2
H nuclear
magnetic resonance (NMR) measurements.
According to the classical approach (Kulkarni et al., 2010), the lipid molecu-
lar volume could be calculated by using the density of the used lipid. There is
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