Nonlamellar Lipid Liquid Crystalline Structures at Interfaces - Self-Assembled Supramolecular Architectures: Lyotropic Liquid Crystals - page 302

the chitosan - modifi ed CPNP may be of interest for mucosal drug delivery
applications. It further confi rms that surface modifi cation of LCNP can be
tailored to enhance interfacial interaction.
10.4.2.3 Leaf Surface Inspired by the enhanced delivery of active ingredi-
ent using LCNP, a recent study (Dong et al., 2011) examines the possibility of
using LCNP to deliver active molecules to hydrophobic plant leaf surfaces.
ATR-FTIR was used to monitor the adsorption of CPNP and hexagonal phase
nanoparticles (HPNP) on model and real leaf surfaces (Fig. 10.9). The study
shows that the adsorption behavior is dependent on the internal nanostruc-
ture, with higher adsorption and delivery effi cacy for the cubic phase particles
than the hexagonal counterpart. The difference in adsorption is explained by
the difference in the gain in free energy due to structural changes (relaxation)
Figure 10.9 ATR - FTIR spectra of cubosome - and hexosome - coated surfaces after
100 min of adsorption. [Reprinted with permission from Dong et al. (2011). Copyright
2011 by the American Chemical Society.]