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15. Georgopapadakou, N. H. (2004) Beta-lactamase inhibitors: evolving compounds
for evolving resistance targets.
Expert Opin. Investig. Drugs
13
, 1307-1318.
16. Rogers, B. L. (2004) Bacterial targets to antimicrobial leads and development
candidates.
Curr. Opin. Drug Discov. Dev
.
7
, 211-222.
17. Halliday, J., McKeveney, D., Muldoon, C., Rajaratnam, P. and Meutermans, W.
(2006) Targeting the forgotten transglycosylases.
Biochem. Pharmacol
.
71
, 957-967.
18. Silver, L. L. (2003) Novel inhibitors of bacterial cell wall synthesis.
Curr. Opin.
Microbiol
.
6
, 431-438.
19. Sutcliffe, J. A. (2005). Improving on nature: antibiotics that target the ribosome.
Curr. Opin. Microbiol
.
8
, 534-542.
20. Alksne, L. E., Anthony, R. A., Liebman, S. W., and Warner, J. R. (1993). An
accuracy center in the ribosome conserved over 2 billion years.
Proc. Natl. Acad.
Sci. U.S.A
.
90
, 9538-9541.
21. Franceschi, F. and Duffy, E. M. (2006) Structure-based drug design meets the
ribosome.
Biochem. Pharmacol
.
71
, 1016-1025.
22. Ebright, R. H. (2000) RNA polymerase: structural similarities between bacterial
RNA polymerase and eukaryotic RNA polymerase II.
J. Mol. Biol
.
304
, 687-98.
23. Bruck, I. and O'Donnell, M. (2000) The DNA replication machine of a gram-
positive organism.
J. Biol. Chem
.
275
, 28971-28983.
24. Bermingham, A. and Derrick, J. P. (2002) The folic acid biosynthesis pathway
in bacteria: evaluation of potential for antibacterial drug discovery.
Bioessays
24
,
637-648.
25. Heath, R. J., White, S. W., and Rock, C. O. (2002) Inhibitors of fatty acid synthesis
as antimicrobial chemotherapeutics.
Appl. Microbiol. Biotechnol
.
58
, 695-703.
26. Zhao, L., Allanson, N. M., Thomson, S. P., Maclean, J. K., Barker, J. J., Primrose,
W. U., Tyler, P. D., and Lewendon, A. (2003) Inhibitors of phosphopantetheine
adenylyltransferase.
Eur. J. Med. Chem
.
38
, 345-349.
27. Hutton, C. A., Southwood, T. J., and Turner, J. J. (2003) Inhibitors of lysine
biosynthesis as antibacterial agents.
Mini Rev. Med. Chem
.
3
, 115-127.
28. Gunderson, C. W. and Segall, A. M. (2006) DNA repair, a novel antibacterial
target: Holliday junction-trapping peptides induce DNA damage and chromosome
segregation defects.
Mol. Microbiol
.
59
, 1129-1148.
29. Pohlmann, J. and Brotz-Oesterhelt, H. (2004) New aminoacyl-tRNA synthetase
inhibitors as antibacterial agents.
Curr. Drug Targets Infect. Disord
.
4
, 261-272.
30. Clements, J. M., Ayscough, A. P., Keavey, K., and East, S. P. (2002) Peptide
deformylase inhibitors, potential for a new class of broad spectrum antibacterials.
Curr. Med. Chem. Antiinfect. Agents
1
, 239-249.
31. Johnson, K. W., Lofland, D., and Moser, H. E. (2005) PDF inhibitors: an emerging
class of antibacterial drugs.
Curr. Drug Targets Infect. Disord
.
5
, 39-52.
32. Leeds, J. A., Schmitt, E. K., and Krastel, P. (2006) Recent developments in
antibacterial drug discovery: microbe-derived natural products-from collection to
the clinic.
Expert Opin. Investig. Drugs
15
, 211-226.
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