Biology Reference
In-Depth Information
Simplified scheme of the source and channels of the flow of the epigenetic
information in eumetazoans
Structures involved in the generation and the
flow of the epigenetic information
Processes involved in the transmission of the epigenetic information
Sensory receptors/organs
Conversion of external/internal stimuli into electrical spike trains
Nonhypothalamic CNS
Processing of the sensory input
Hypothalamus (other brain centers)
Secretion of releasing (other) hormones
Secretion of stimulating hormones
Pituitary gland
Target endocrine glands
Secretion of endocrine hormones
Secretion of growth factors,
secreted proteins, etc.
Cell membrane
Binding to specific membrane receptors
Signal transduction pathway
Epigenetic marks
Expression of
nonhousekeeping genes
Cell nucleus
Figure 5.16
Simplified model of generation and flow of epigenetic information for expression of systemic genes in response
to external or internal stimuli in vertebrates.
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