Biomedical Engineering Reference
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(a)
(b)
{111}
<001>
<110>
{111}
{111}
<111>
Double
twins
{111}
{111}
<110>
<001>
(c)
(d)
<110>
{111}
<001>
{111}
<111
Single
twin
{111}
<001>
50 nm
<110>
Fig. 4
Structural analysis of gold nanocrosses.
a
Low-magnification TEM and
b
HRTEM
images of a doubly twinned gold nanocross with D
2h
symmetry. The inset in
a
shows one set of
SAED spots.
c
Low-magnification TEM and
d
HRTEM images of a singly twinned gold nano-
cross with C
2v
symmetry. The inset in
c
shows two sets of SAED spots, labeled with
squares
and
circles
. This image is reproduced from [
94
] with permission
membrane based drug delivery system consisting of PNIPAAM hydrogel (Fig.
5
)
[
97
]. The engineered hybrid system was synthesized by co-evaporation to cause
the entrapment of PNIPAAM and iron oxide nanoparticles to give a presumably
disordered network. The obtained device enabled rapid, repeatable, and tunable
drug delivery through the swelling and deswelling transition of PNIPAAM nano-
gel upon the application of an external oscillating magnetic field. Analysis with
sodium flurorescein showed approximately 20-fold increase in flux when the
device was turned “on” by exposure to an oscillating magnetic field, as well as
consistent drug flux over four on-off cycles.
Fig. 5
Schematic illustration
of drug delivery from
magnetically triggered
cellulose-iron oxide particle
hybrid membrane consisting
of PNIPAAM-based nanogels
(this image is enhanced and
reproduced from [
97
] with
permission)
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