Environmental Engineering Reference
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Figure 2. Microarray screening of detoxifications genes differentially transcribed in the insecticide-
resistant strain Vauclin. Differential transcription of detoxification gens was investigated separately in
4th-stage larvae (A) and 3-days old adults (B). For each life stage, differences in gene transcription are
indicated as a function of both transcription ratio (Vauclin/Bora-Bora) and ratio's significance (t-test
P values). For each comparison, only probes showing consistent data in at least three hybridizations
out of six were considered. Vertical lines indicate 1.5-fold transcription difference in either direction.
Horizontal line indicates significance threshold (p < 0.01) adopted for the one sample t-test after
Benjamini and Hochberg multiple testing correction procedure. Probes showing both more than 1.5-
fold differential transcription and a significant P value are named. Probes that were found under- or
over-transcribed in both larvae and adults are shown in bold. Suffixes a and b represent two different
probes of the same gene while suffixes v1 and v2 represent two different alleles of the same gene.
 
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