Biomedical Engineering Reference
In-Depth Information
cell mechanics, tissue engineering, along with cellular and molecular biology and
imaging in order to better understand the key cellular mechanisms and signaling
pathways that are involved in these processes. The impact of such research would
be vast, not only in basic science but also in uncovering the factors responsible for
the development of obesity and related pathologies, and finding the appropriate
and most effective preventive and treatment measures.
Acknowledgements This research work is being supported by a Grant from the Israel Science
Foundation (no. 611/12, A.G. and D.B.) and by the Israel Ministry of Science and Technology
(Women in Science Scholarship awarded to N.S.).
References
1. Alkhouri, N., Gornicka, A., Berk, M.P., Thapaliya, S., Dixon, L.J., Kashyap, S., Schauer,
P.R., Feldstein, A.E.: Adipocyte apoptosis, a link between obesity, insulin resistance, and
hepatic steatosis. J. Biol. Chem. 285, 3428-3438 (2010)
2. Anderson, L.A., McTernan, P.G., Barnett, A.H., Kumar, S.: The effects of androgens and
estrogens on preadipocyte proliferation in human adipose tissue: influence of gender and site.
J. Clin. Endocrinol. Metab. 86, 5045-5051 (2001)
3. Ben-Or, M., Shoham, N., Lin, F.H., Gefen, A.: Influence of the extracellular matrix stiffness
in
tissue-engineered
constructs
on
deformed
cell
shapes
under
large
compressive
deformations. J. Biomater Tissue Eng. 3, 1-4 (2013)
4. Bishitz, Y., Gabai, H., Girshovitz, P., Shaked, N.T.: Optical-mechanical signatures of cancer
cells based on fluctuation profiles measured by interferometry. J. Biophotonics (2013).
5. Case, N., Xie, Z., Sen, B., Styner, M., Zou, M., O'Conor, C., Horowitz, M., Rubin, J.:
Mechanical activation of b-catenin regulates phenotype in adult murine marrow-derived
mesenchymal stem cells. J. Orthop. Res. 28, 1531-1538 (2010)
6. Chiu, Y.C., Cheng, M.H., Uriel, S., Brey, E.M.: Materials for engineering vascularized
adipose tissue. J. Tissue Viability 20, 37-48 (2011)
7. Cinti, S.: Adipocyte differentiation and transdifferentiation: plasticity of the adipose organ.
J. Endocrinol. Invest. 25, 823-835 (2002)
8. Cinti, S.: Between brown and white: novel aspects of adipocyte differentiation. Ann. Med. 43,
104-115 (2011)
9. Cinti, S.: The adipose organ. Prostaglandins Leukot. Essent. Fatty Acids 73, 9-15 (2005)
10. Cooke, P.S., Naaz, A.: Role of estrogens in adipocyte development and function. Exp. Biol.
Med. 229, 1127-1135 (2004). (Maywood)
11. Cooper, S.C., Roncari, D.A.: 17-beta-estradiol increases mitogenic activity of medium from
cultured preadipocytes of massively obese persons. J. Clin. Invest. 83, 1925-1929 (1989)
12. Cutler Jr, G.B.: The role of estrogen in bone growth and maturation during childhood and
adolescence. J. Steroid Biochem. Mol. Biol. 61, 141-144 (1997)
13. Darling, E.M., Topel, M., Zauscher, S., Vail, T.P., Guilak, F.: Viscoelastic properties of
human
mesenchymally-derived
stem
cells
and
primary
osteoblasts,
chondrocytes,
and
adipocytes. J. Biomech. 41, 454-464 (2008)
14. David, V., Martin, A., Lafage-Proust, M.H., Malaval, L., Peyroche, S., Jones, D.B., Vico, L.,
Guignandon, A.: Mechanical loading down-regulates peroxisome proliferator-activated
receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of
adipogenesis. Endocrinology 148, 2553-2562 (2007)
Search WWH ::
Custom Search