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4.5 SUMMARY
In this chapter, S N 2 reaction mechanisms were defined and presented in the context of
nucleophiles displacing leaving groups at electrophilic centers. Furthermore, the conditions
required for S N 2 reactions to proceed were discussed as well as factors that influence the
progression of such reactions. In this context, discussions of S N 2 reactions were extended
into the related S N 2 0 reaction mechanisms.
As the principles of this chapter, by nature, build upon those presented in previous
chapters, the same will be for topics discussed in the remainder of this topic. The study
of organic chemistry is a progressive task with many overlapping principles. As should
be apparent from topics discussed thus far, many of these principles reduce to the acid-
base chemistry presented in the earliest chapters. This is also the case for the remaining
topics presented herein.
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