Chemistry Reference
In-Depth Information
Swern oxidation is shown in Problem 3(d) of this chapter, the mechanism for the
Horner-Emmons reaction is shown in Problem 2(c) of this chapter, and the mech-
anism for base-mediated ester hydrolysis was highlighted in Scheme 7.19.
Methyl salicylate, the active flavor compound in wintergreen candy, is composed
of two fragments resembling structures from the above list of compounds. These
fragments are illustrated below and relate to salicylic acid and methyl alcohol.
The combination of these compounds will generate methyl salicylate when con-
ditions for an acid-mediated esterification, illustrated below, are applied. The
