Chemistry Reference
In-Depth Information
This is an addition-elimination reaction of methanol with acetyl chloride forming
methyl acetate. As illustrated below using arrow pushing, methanol is being added
while hydrochloric acid is being eliminated. The driving force behind this reaction
lies with the relative electronegativities of chlorine and oxygen. Chlorine being
more electronegative than oxygen translates to a chlorine anion (chloride) being
a better leaving group than an oxygen anion (alkoxide).
This is an addition-elimination reaction of methylamine with acetyl chloride
forming methyl acetamide. As illustrated below using arrow pushing, methylamine
is being added while hydrochloric acid is being eliminated. The driving force
behind this reaction lies with the relative electronegativities of chlorine and nitro-
gen. Chlorine being more electronegative than nitrogen translates to a chlorine
anion (chloride) being a better leaving group than a nitrogen anion (amide).
This is an addition-elimination reaction of methylamine with methyl acetate
forming methyl acetamide. As illustrated below using arrow pushing, methylamine
is being added while methanol is being eliminated. The driving force behind this
reaction lies with the relative electronegativities of oxygen and nitrogen. Oxygen
