Chemistry Reference
In-Depth Information
The first step of this reaction is deprotonation of the alcohol with sodium hydride.
The second step of this reaction is an intramolecular S
N
2
0
reaction with the alkoxide
anion displacing the bromide anion through the double bond.
This reaction is an S
N
2
0
displacement of an alkoxide anion through the double bond.
10.
a
,
b
-unsaturated carbonyls are readily formed from the corresponding
b
-hydroxy
ketones. Explain the product of the following reaction:
Upon examining the reaction, the initial phase of this sequence can be defined as an
aldol condensation [see Problem 8(a)]. Under the specified conditions, hydride is
