Chemistry Reference
In-Depth Information
According to Appendix 1, the pK
a
value for an alkane proton is approximately 50-
75, and the pK
a
value for a carbonyl-protonated amide is approximately 0. Therefore,
the order of protonation is as follows:
According to Appendix 1, the pK
a
value for an alkane proton is approximately 50-
75, the pK
a
value for a vinyl proton is approximately 35-40, the pK
a
value for an
acetylene proton is approximately 25, and the pK
a
value for an alcohol is approxi-
mately 15-19. Therefore, the order of protonation is as follows:
According to Appendix 1, the pK
a
value for a protonated nitrile is approximately
2
10, the pK
a
value for a carbonyl-protonated ester is approximately
2
6, and the
pK
a
value for a protonated alcohol is approximately
2
2. Therefore, the order of pro-
tonation is as follows:
