Ascaris and Allergy - Ascaris: The Neglected Parasite - page 46

157. Sironi M, Clerici M. The hygiene hypothesis: an evolutionary perspective. Microbes
Infect 2010;12:421 e 7.
158. Jackson JA, Friberg IM, Little S, Bradley JE. Review series on helminths, immune
modulation and the hygiene hypothesis: immunity against helminths and immuno-
logical phenomena in modern human populations: coevolutionary legacies? Immu-
nology 2009;126:18 e 27.
159. Fumagalli M, Pozzoli U, Cagliani R, et al. Parasites represent a major selective force for
interleukin genes and shape the genetic predisposition to autoimmune conditions.
J Exp Med 2009;206:1395 e 408.
160. Fumagalli M, Pozzoli U, Cagliani R, et al. The landscape of human genes involved in
the immune response to parasitic worms. BMC Evol Biol 2010;10:264.
161. Barreiro LB, Quintana-Murci L. From evolutionary genetics to human immunology:
how selection shapes host defence genes. Nat Rev Genet 2010;11:17 e 30.
162. Lynch NR, Hagel IA, Palenque ME, et al. Relationship between helminthic infection
and IgE response in atopic and nonatopic children in a tropical environment. J Allergy
Clin Immunol 1998;101:217 e 21.
163. Cooper PJ, Chico ME, Sandoval C, Nutman TB. Atopic phenotype is an important
determinant of immunoglobulin E-mediated inflammation and expression of T helper
cell type 2 cytokines to ascaris antigens in children exposed to ascariasis. J Infect Dis
2004;190:1338 e 46.
164. Cooper PJ. Intestinal worms and human allergy. Parasite Immunol 2004;26:455 e 67.
165. Le Souef PN, Goldblatt J, Lynch NR. Evolutionary adaptation of inflammatory immune
responses in human beings. Lancet 2000;356:242 e 4.
166. Hopkin J. Immune and genetic aspects of asthma, allergy and parasitic worm infec-
tions: evolutionary links. Parasite Immunol 2009;31:267 e 73.
167. May RM, Anderson RM. Epidemiology and genetics in the coevolution of parasites
and hosts. Proc R Soc Lond Series B, containing papers of a biological character 1983;219:
281 e 313.
168. Dunne DW, Cooke A. A worm's eye view of the immune system: consequences for
evolution of human autoimmune disease. Nat Rev Immunol 2005;5:420 e 6.
169. Peisong G, Yamasaki A, Mao XQ, et al. An asthma-associated genetic variant of STAT6
predicts low burden of Ascaris worm infestation. Genes Immun 2004;5:58 e 62.
170. Moller M, Gravenor MB, Roberts SE, Sun D, Gao P, Hopkin JM. Genetic haplotypes of
Th-2 immune signalling link allergy to enhanced protection to parasitic worms. Hum
Mol Genet 2007;16:1828 e 36.
171. Acevedo N, Mercado D, Vergara C, et al. Association between total immunoglobulin E
and antibody responses to naturally acquired Ascaris lumbricoides infection and poly-
morphisms of immune system-related LIG4, TNFSF13B and IRS2 genes. Clin Exp
Immunol 2009;157:282 e 90.
172. Williams-Blangero S, VandeBerg JL, Subedi J, et al. Genes on chromosomes 1 and 13
have significant effects on Ascaris infection. Proc Natl Acad Sci USA 2002;99:5533 e 8.
173. Williams-Blangero S, Vandeberg JL, Subedi J, Jha B, Correa-Oliveira R, Blangero J.
Localization of multiple quantitative trait loci influencing susceptibility to infection
with Ascaris lumbricoides . J Infect Dis 2008;197:66 e 71.
174. Feary JR, Venn AJ, Mortimer K, et al. Experimental hookworm infection: a randomized
placebo-controlled trial in asthma. Clin Exp Allergy 2010;40:299 e 306.
175. Bager P, Kapel C, Roepstorff A, et al. Symptoms after ingestion of pig whipworm
Trichuris suis eggs in a randomized placebo-controlled double-blind clinical trial. PLoS
One 2011;6:e22346.
176. Oshiro TM, Enobe CS, Araujo CA, Macedo MS, Macedo-Soares MF. PAS-1, a protein
affinity purified from Ascaris suum worms, maintains the ability to modulate the
immune response to a bystander antigen. Immunol Cell Biol 2006;84:138 e 44.