Diagnosis and Control of Ascariasis in Pigs - Ascaris: The Neglected Parasite - page 397

TABLE 16.3 Overview of the vaccination experiments performed against A. suum

Year Antigen Immunization protocol Host Recovered stage % Reduction Reference

1978 UV-eggs 3 oral inoculations with 500 UV-eggs Pigs Adults 86% a

1982 UV-eggs 3 oral inoculations with 10,000 UV- eggs Pigs Lung larvae 88% b

1984 UV-eggs 2 e 5 oral inoculations with

100 e 10,000 UV-eggs

Pigs Lung larvae 83 e 94% c

1985 Hatching fluid

L3 ES
L3/4 ES
UV-eggs

A number of immunization experiments
using different antigens

Pigs Lung larvae Max 80% 37

alum w/wo
oral inoculation with UV-eggs

þ

1988 L3 larval body wall 2 oral immunizations with antigen

in liposome complex, w/wo priming
egg dose

Pigs Lung larvae and

L5/adults

N.S. d

1992 Adult crude antigen 2 s.c. immunizations with the antigen

in a liposome, w/wo immunomodulator

Mice Lung and liver

larvae together

89% e

1994 L3 cuticle Ag

adult cuticle Ag
UV-eggs

1 i.m. immunizations with antigen FIA

and 2 i.p. immunizations with antigen
þ

þ Pigs Lung larvae 49%

44%
89%

f

alum
Or, 1 oral inoculation with 10,000
UV-eggs

( Continued )