Biology Reference
In-Depth Information
TABLE 7.1 Ranges of efficacies (%) of albendazole (ABZ), mebendazole (MBZ), pyrantel (PYR), ivermectin (IVM) and diethylcarbamazine
(DEC)
IVM
(150
ABZ
D
IVM
DEC (150 mg)
(6 mg/kg)
Species
ABZ (
400 mg)
MBZ (500 mg)
PYR (10 mg/kg)
e
200
g/kg)
ABZ
D
DEC
‡
m
100
241,242
100
241,242
100
241,242
78
241,243
ERR 94
243
Ascaris lumbricoides
CR 67
e
CR 91
e
CR 79
e
CR 50
e
CR 78;
ERR 100
243
CR 24;
ERR 34
243
100
242,243
99
242
ERR 87
e
ERR 96
e
CR 78;
ERR 97
243
CR 31;
ERR 77
244
77
241,242
100
241,242
56
241
80
241,243
ERR 87
243
Trichuris trichiura
CR 10
e
CR 16
e
CR 0
e
CR 11
e
CR 65;
ERR 98
243
CR 3;
ERR 20
243
90
242,243
93
242
ERR 0
e
ERR 81
e
CR 19;
ERR 79
243
CR 77;
ERR 86
244
95
241,242
100
241
88
241,242
20
241
Necator americanus,
Ancylostoma duodenale
CR 33
e
CR 95
e
CR 19
e
CR 0
e
100
3
ERR 64
e
CR 1
e
27;
98
242
ERR 0
e
CR 90;
ERR 94
244
CR 26;
ERR 36
244
Abbreviations: CR, cure rate (proportion of treated individuals who became parasitologically negative); ERR, egg reduction rate (proportion reduction in egg count from
baseline). Adapted from Bas´˜ ez et al.
113
