Biomedical Engineering Reference
In-Depth Information
Mechanical properties of body fluids, tissues, cells and organs (some topics to
think about)
• Body Fluid mechanics (blood, plasma, interstitial fluid) (friction, lamination,
microfluidics)
• Cellular mechanics (shear stress, elasticity, plasticity)
• Mechanical properties of cytoskeleton (complex)
• Tissue and organ mechanics (complex)
• Bones (brittle, elastic)
• Connective tissues (elastic, plastic)
• Lungs (elastic)
Emphasizing Bioengineering Aspects to Cell Biomechanics
Efforts from Kubo Laboratory
In order to create the world's leading-edge system and material technology for next-
generation, the simulation and theoretical design of chemical reaction, structure,
fluid, function, property, etc. is strongly required [
6
-
20
] (
http://www.kubo.rift.mech.
tohoku.ac.jp/eng/
)
. Especially, the recent system, process, and material technologies
are progressing toward the super-precision and super-miniaturization and constitute
of the complicated multi-physics phenomena including chemical reaction, friction,
impact, stress, fluid, photon, electron, heat, electric and magnetic fields, etc. [
9
-
11
].
Therefore, the individual and simple understanding of the chemical reaction, structure,
and luid on atomic-scale as well as the function and property on ʼm/cm/m-scale is
insufficient for the development of the next-generation system and material, and then
the multiple and deep understanding of the above complicated multi-physics phe-
nomena are significantly essential. However, the traditional mechanical engineering
is based on the macroscopic science and continuum approach such as the mechanics
of machinery, mechanics of material, fluid mechanics, and thermodynamics and then
it cannot solve the recent problems and not investigate the leading-edge research
themes in a wide range of research fields because the multi-physics phenomena on
electronic- and atomic-scale extremely affect the macro-scale function and perfor-
mance in the state-of-the-art technologies [
12
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20
] (
http://www.kubo.rift.mech.
Therefore, Kubo laboratory aims to pioneer and develop the multi-physics com-
putational science simulation technology based on the first-principles molecular
dynamics and SCF-tight-binding molecular dynamics simulation for clarifying the
multi-physics phenomena including chemical reaction, friction, impact, stress, fluid,
photon, electron, heat, electronic and magnetic fields on atomic- and electronic-scale
(see Fig.
15.15
).
