Biology Reference
In-Depth Information
TABLE 1
Selectivity of commercially available lectins
Lectin name
Group specificity
Glycan(s) selected
a
/
b
-D-galactosyl-speci
Gal
b
1-3GalNAc-serine/
threonine
Agaricus bisporus (ABA)
c
llomyrina dichotoma (AlloA)
a
/
b
-D-galactosyl-speci
c
NeuAc
a
2-3G
a
l
b
1-4GlcNAc
Artocarpus integrifolia (Jacalin)
a
/
b
-D-galactosyl-speci
c
Gal
b
1-3GalNAc, Gal
a
1-6 Gal
Erythrina christagalli (ECA)
a
/
b
-D-galactosyl-speci
c
Gal
b
1-4GlcNAc
Arachis hypogaea (peanut, PNA)
a
/
b
-D-galactosyl-speci
c
Gal
b
1-3GalNAc
Dolichos bi
orus (DBA)
D-N-acetylgalactosaminyl-speci
c
GalNAc
a
1-3GalNAc;
GalNAc
a
1-3Gal
Glycine max (soybean, SBA)
D-N-acetylgalactosaminyl-speci
c
GalNAc
a
1-3GalNAc;
GalNAc
a
/
b
1-3/4 Gal
Helix pomatia (HPA)
D-N-acetylgalactosaminyl-speci
c
a
-GalNAc, GalNAc
b
1-4 Gal
Phaseolus lunatus
(lima bean, LBA)
D-N-acetylgalactosaminyl-speci
c
GalNAc
a
1-3(Fuc
a
1-2)Gal
b
;
GalNAc
a
1-2Gal
b
Wisteria
floribunda (WFA)
D-N-acetylgalactosaminyl-speci
c
GalNAc
a
1-3GalNAc;
GalNAc
b
1-3/4 Gal
Vicia villosa (VVA)
D-N-acetylgalactosaminyl-speci
c
GalNAc-Ser
Datura stramonium (DSA)
D-N-acetylglucosamine-speci
c
(GlcNAc
b
1-4)
2-4
;
Gal
b
1-4GlcNAc
Griffonia simpli
lica II (GS-II)
D-N-acetylglucosamine-speci
c
GlcNAc
a
1-4Gal
b
1-4GlcNAc
(GlcNAc
b
1-4)
1-4
Lycopersicon esculentum (Tomato)
D-N-acetylglucosamine-speci
c
Triticum vulgare
(wheat germ, WGA)
D-N-acetylglucosamine-speci
c
(GlcNAc
b
1-4)
2-5;
Neu5Ac;
Man
b
1-4GlcNAc
b
1-4GlacNAc
Canavalia ensiformis (Con A)
D-mannosyl-speci
c
Branched N-linked
hexasaccharide
Galanthus nivalis (GNA)
D-mannosyl-speci
c
Man
a
1-3Man; Fuc-
a
1-
6GlcNAc-N-Asn containing
Lens culinaris (LCA)
D-mannosyl-speci
c
N-linked; Fuc
a
1-6GlcNAc-
N-Asn containing
Pisum sativum (PSA)
D-mannosyl-speci
c
N-linked oligosaccharides
Aleuria aurantia (AAL)
a
-L-Fucosyl-speci
c
Fuc
a
1-6/3GlcNAc
Anguilla anguilla (AAA)
a
-L-Fucosyl-speci
c
a
-L-Fuc
Lotus tetragonolobus (LCA)
a
-L-Fucosyl-speci
c
Fuc
a
1-2Gal
b
1-4(Fuc
a
1-3)
GlcNAc
Ulex europaeus I (UEA I)
a
-L-Fucosyl-speci
c
Fuc
a
1-2Gal
b
Cancer antennarius (CAA)
Neu5Ac-speci
c
4/9-O-Ac-Neu5Ac
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