Biology Reference
In-Depth Information
essential to synthesize such a cell. The advancement of high-throughput technologies has
certainly aided in the understanding of these mechanisms. However, the lack of efficient
methods to extract new information from the overwhelming volume of new data has
bottlenecked the advancement. With the development of new synthetic biology components
and tools targeting specific cellular components/functions, the high-throughput data can be
translated into new knowledge and information. In addition to modifying genetic
components of the cell, a systems-level analysis of what these modifications will do to the
physiology of the cell is necessary to allow the cell to optimally perform the task for which
is has been engineered.
Acknowledgments
This work was supported by the Technology Development Program to Solve Climate Changes on Systems
Metabolic Engineering for Biorefineries (NRF-2012-C1AAA001-2012M1A2A2026556) of the Ministry of Education,
Science and Technology (MEST) through the National Research Foundation (NRF). Further support by the
Intelligent Synthetic Biology Center (2011-0031963) of the Global Frontier Project and the World Class University
Program (R32-2009-000-10142-0) of MEST through the NRF is appreciated.
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