Biomedical Engineering Reference
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momentum equation has been solved, the pressure can be recovered by solving the
least square problem in the full Finite Element space, that is,
p h D
q h 2 Q h jjf h C u h B T qjj
2 :
min
(6.76)
The solution to this problem exists and is unique, provided that the velocity and
pressure FE spaces satisfy the inf-sup condition, which guarantees that B T has
full column rank. In order to have a representation of the pressure in the reduced
space, one has to make sure that the reduced saddle point problem is non-singular.
In literature this issue has been tackled by enriching the velocity reduced space [ 64 ].
We therefore construct the reduced basis only for the fluid velocity and mem-
brane displacement fields. To this end, we solve the forward problem for a given
set of Young moduli E 1 ;:::;E M and store the corresponding solutions (snapshots)
u h;i ; h;i . In order to deal with nonhomogeneous boundary conditions at the
inflow/outflow sections, we modify the velocity snapshots in the following way
u h;i D u h;i u `
(6.77)
where u ` is the solution of a steady rigid-wall Stokes problem used as a lifting
function for the nonhomogeneous boundary conditions. This choice allows us
to preserve the divergence-free nature of the snapshots which are then collected
(amended by the lifting) in the snapshots matrices X u and X . We compute the SVD
of these matrices and let W Ǜ be the matrices containing the first k Ǜ left singular
vectors of X Ǜ (Ǜ D u ;), with k Ǜ such that
i N Ǜ
X
k Ǜ
X
i
(6.78)
i D 1
i D 1
where i are the singular values of X Ǜ , is the fraction of data variability that we
want to capture (typically we take D 0:9;0:95 or 0:99)and
N Ǜ is the dimension
of the FE space. The columns of W u and W form the reduced basis for the fluid
velocity and membrane displacement spaces.
If we project the IFMI problem ( 6.74 ) onto the reduced space, we then obtain
1
2 jj r;h d r jj
E h D arg min
E h 2R
r .E h / D
2
k J
C R
.E h /
" f r;h
n 1
r;h
#
s.t. C r O
tP r I
u r
r
(6.79)
D
where C r D W u CW u ,M r D W T M W ,P r D W T PW u , f r;h D W u .f h B T p h /,
d r;h D W T h meas , and the dependence of C and f h on E is understood for brevity.
The minimization problem is then solved as in the previous section, using the
BFGS method. In particular, in order to evaluate the functional and its gradient, we
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