Biomedical Engineering Reference
In-Depth Information
In the linearized formulation H and M are related by the following additive noise
relation
U C D M
)
Z H C D M :
(6.57)
Here, the observation operator between H and M (see the example in Sect. 6.2.2
for Gaussian vectors) is actually the inverse of a (discrete) differential operator;
Z D DS 1 R in M in has been introduced after ( 6.52 ) and it describes the deterministic
relation between the velocity and the normal stress. The random variable accounts
for the measurement noise. We make the assumption of mutual independence of U
and .Since H and U are related by a linear relation this implies the independence
of H and . As a consequence, the p.d.f. of is independent of any realization of H
and the likelihood function, p M j H , can be expressed as
p M j H .M/ D p M j H . C ZH/D p .M ZH/:
(6.58)
Next, we consider the realization M D d (the vector of available velocity measures
introduced previously), we have
p H j M .H/ / p M j H . d /p H .H/ D p . d ZH/p H .H/:
(6.59)
Now we make the assumption that all variables are Gaussian and we define the a
priori distribution and the noise distribution as follows:
p H D g H / exp
2 .H H 0 / T ƒ H .H H 0 / ;
1
p D g / exp
2 . 0 / T ƒ 1 . 0 /
(6.60)
1
I
where H 0 and 0 are the expectation values and ƒ H and ƒ are the correlation
matrices for H and , respectively. The analysis of Sect. 6.2.2 shows that the
posterior distribution p H j M is a Gaussian distribution itself with covariance and
mean given by
ƒ H j M D .ƒ H C Z T ƒ 1 Z/ 1 ;
E
(6.61)
. H / D ƒ H j M .Z T ƒ 1 . d 0 / C ƒ H H 0 /:
We recall that the mean value of the posterior distribution is the value that maximizes
p H j M , and then, by definition, it is the MAP estimator of H ,say H MAP .Onthe
other hand, the value that maximizes the likelihood function, with respect to H,
corresponds to the ML estimator for H and has the following expression
H ML D .Z T ƒ 1 Z/ 1 .Z T ƒ 1 . d 0 //:
(6.62)
In treating the nonlinearity we consider an iterative approach similar to the
deterministic one described in the previous section; in fact, also in this case, we
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