Biomedical Engineering Reference
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where ı 1 is an admissible variation. We find
!
Z
X
K
u C b r u C u C u 3
ı 1
Ǜ i f i
D 0:
i D 1
Since ı 1 is arbitrary, from this equation we promptly obtain the state prob-
lem ( 6.30 ). Similarly,
LJ LJ LJ LJ 2
Z
" L
. u ;˛;; 1 ; 2 / D
L
@ 2
@
1
2 / D
lim
" ! 0
. u ;˛;; 1 ; 2 C"ı 2 / L
ı 2 u D0
(6.41)
leading to ( 6.31 ).
Let us write explicitly now the adjoint equation
LJ LJ LJ LJ u
@
@ u
1
" .
u / D
lim
" ! 0
L
. u C "ı u ;˛;; 1 ; 2 / L
. u ;˛;; 1 ; 2 //
Z
Z
1 ı u C b u C ı u C 3 u 2 ı u
D
. u d/ı u
Z
2 ı u D 0:
(6.42)
Let us factor out the arbitrary variation ı u . If we integrate by parts the second and
first order terms, we get
Z
ı u u d C 1 C b r 1 1 3 u 2 1
Z
Z
C
1 u n
.r 1 n C 1 b n C 2 u D 0:
Because ı u is arbitrary, this equation is equivalent to
1 b r 1 C 1 C 3 u 2 1 D u d in
1 D 0
on
2 D b r 1 n 1 n
on :
Notice that 2 does not affect the solution of the problem, therefore in the following
we drop the last equation because we are not interested in the particular value
assumed by 2 . Finally, we compute the derivative with respect to the control
 
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