Biomedical Engineering Reference
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where 2 D 2 and 3 D . On the other hand, we rewrite:
Z
Z 2
Z
nl d 2 d 0 dx d :
nd D
@ l n .@B 1 [ @B 2 /
1
j .x 1 ;:::;x d 1 / jD l
Here “d 0 D ı x 1 D l C ı x 1 D l ” in the two-dimensional case and “d 0 =d ”
corresponding to cylindrical coordinates .r;; z / associated with .x 1 ;x 2 ;x 3 / in the
three-dimensional case. We note that:
Z
nd 0 D 0:
j .x 1 ;:::;x d 1 / jD l;x d D 1 .l/
Consequently, we bound from above the lateral flux by combining a Hölder
inequality with a Poincaré inequality:
LJ LJ LJ LJ
nd LJ LJ LJ LJ
Z
@ l n .@B 1 [ @B 2 /
. 2 .l/ 1 .l// 2 p l .d 2/.1 p / Z
p d
1
p
j .x 1 ;:::;x d 1 / jD l jrj
: (4.73)
Finally, introducing ( 4.72 )and( 4.73 )into( 4.71 ) yields:
j d l d 1 Œ. 2 1 / e d j
p / Z
p d
1
p
1
p l .d 2/.1
1
. 2 .l/ 1 .l// 2
j .x 1 ;:::;x d 1 / jD l jrj
:
We can now integrate this identity between l D 0 and l D r 2 .0;ı/.As 2 1 is
non-decreasing, this entails that:
1
p r .d 1/.1
1
p / d
jŒ. 2 1 / e d jC. 2 .r/ 1 .r// 2
krI L p . R d /k;
w ith a constant C depending on d.Forh sufficiently small, we might choose r D
p h to obtain:
1
2 .3 .d C 1/ p /
jŒ. 2 1 / e d j Ch
krI L p . R d /k;
C depends now on d and ı.
where
t
We conclude the proof of Theorem 4.3 , item (i), as follows. Assume that the
distance dŒf B i .t/g i D 0;:::;n goes to 0 for a sequence of time t ! T . Then, by
a compactness argument, there exist X 1 and X 2 such that B.X 1 ;ı/ B
i and
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