Biomedical Engineering Reference
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where
2
D 2 and
3
D . On the other hand, we rewrite:
Z
Z
2
Z
nl
d
2
d
0
dx
d
:
nd D
@
l
n
.@B
1
[
@B
2
/
1
j
.x
1
;:::;x
d
1
/
jD
l
Here “d
0
D ı
x
1
D
l
C ı
x
1
D
l
” in the two-dimensional case and “d
0
=d ”
corresponding to cylindrical coordinates .r;;
z
/ associated with .x
1
;x
2
;x
3
/ in the
three-dimensional case. We note that:
Z
nd
0
D 0:
j
.x
1
;:::;x
d
1
/
jD
l;x
d
D
1
.l/
Consequently, we bound from above the lateral flux by combining a Hölder
inequality with a Poincaré inequality:
LJ
LJ
LJ
LJ
nd
LJ
LJ
LJ
LJ
Z
@
l
n
.@B
1
[
@B
2
/
.
2
.l/
1
.l//
2
p
l
.d
2/.1
p
/
Z
p
d
1
p
j
.x
1
;:::;x
d
1
/
jD
l
jrj
: (4.73)
Finally, introducing (
4.72
)and(
4.73
)into(
4.71
) yields:
j
d
l
d
1
Œ.
2
1
/ e
d
j
p
/
Z
p
d
1
p
1
p
l
.d
2/.1
1
.
2
.l/
1
.l//
2
j
.x
1
;:::;x
d
1
/
jD
l
jrj
:
We can now integrate this identity between l D 0 and l D r 2 .0;ı/.As
2
1
is
non-decreasing, this entails that:
1
p
r
.d
1/.1
1
p
/
d
jŒ.
2
1
/ e
d
jC.
2
.r/
1
.r//
2
krI L
p
.
R
d
/k;
w
ith
a constant C depending on d.Forh sufficiently small, we might choose r D
p
h to obtain:
1
2
.3
.d
C
1/
p
/
jŒ.
2
1
/ e
d
j Ch
krI L
p
.
R
d
/k;
C depends now on d and ı.
where
t
We conclude the proof of Theorem
4.3
, item (i), as follows. Assume that the
distance dŒf
B
i
.t/g
i
D
0;:::;n
goes to 0 for a sequence of time t ! T
. Then, by
a compactness argument, there exist X
1
and X
2
such that B.X
1
;ı/
B
i
and
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