Biology Reference
In-Depth Information
[53] Roemer T, Davies J, Giaever G, Nislow C. Bugs, drugs and
chemical genomics. Nat Chem Biol 2011;8:46
[70] Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG,
Ahringer J. Effectiveness of specific RNA-mediated interference
through ingested double-stranded RNA in Caenorhabditis ele-
gans. Genome Biol 2001;2:RESEARCH0002.
[71] Timmons L, Court DL, Fire A. Ingestion of bacterially expressed
dsRNAs can produce specific and potent genetic interference in
Caenorhabditis elegans. Gene 2001;263:103 e 12.
[72] Timmons L, Fire A. Specific interference by ingested dsRNA.
Nature 1998;395:854.
[73] Poulin G, Dong Y, Fraser AG, Hopper NA, Ahringer J. Chromatin
regulation and sumoylation in the inhibition of Ras-induced
vulval development
56.
[54] Burns AR, Wallace IM, Wildenhain J, Tyers M, Giaever G,
Bader GD, et al. A predictive model for drug bioaccumulation and
bioactivity in Caenorhabditis elegans. Nat Chem Biol 2010;
6:549 e 57.
[55] Burns AR, Kwok TC, Howard A, Houston E, Johanson K,
Chan A, et al. High-throughput screening of small molecules for
bioactivity and target identification in Caenorhabditis elegans.
Nat Protoc 2006;1:1906 e 14.
[56] Kwok TC, Ricker N, Fraser R, Chan AW, Burns A, Stanley EF,
et al. A small-molecule screen in C. elegans yields a new calcium
channel antagonist. Nature 2006;441:91 e 5.
[57] Luciani GM, Magomedova L, Puckrin R, Urbanus ML,
Wallace IM, Giaever G, et al. Dafadine inhibits DAF-9 to promote
dauer formation and longevity of Caenorhabditis elegans. Nat
Chem Biol 2012;8:318.
[58] Kim DU, Hayles J, Kim D, Wood V, Park HO, Won M, et al.
Analysis of a genome-wide set of gene deletions in the fission yeast
Schizosaccharomyces pombe. Nat Biotechnol 2010;28:617 e 23.
[59] Winzeler EA, Shoemaker DD, Astromoff A, Liang H,
Anderson K, Andre B, et al. Functional characterization of the
S. cerevisiae genome by gene deletion and parallel analysis.
Science 1999;285:901 e 6.
e
in Caenorhabditis
elegans.EMBOJ
2005;24:2613 e 23.
[74] Sieburth D, Ch'ng Q, Dybbs M, Tavazoie M, Kennedy S,
Wang D, et al. Systematic analysis of genes required for synapse
structure and function. Nature 2005;436:510 e 7.
[75] Kim JK, Gabel HW, Kamath RS, Tewari M, Pasquinelli A,
Rual JF, et al. Functional genomic analysis of RNA interference in
C. elegans. Science 2005;308:1164 e 7.
[76] Harris TW, Antoshechkin I, Bieri T, Blasiar D, Chan J, Chen WJ,
et al. WormBase: a comprehensive resource for nematode
research. Nucleic Acids Res 2010;38:D463 e 467.
[77] Yook K, Harris TW, Bieri T, Cabunoc A, Chan J, Chen WJ, et al.
WormBase 2012: more genomes, more data, new website. Nucleic
Acids Res 2012;40:D735
[60]
Jones GM, Stalker J, Humphray S, West A, Cox T, Rogers J, et al.
A systematic library for comprehensive overexpression screens in
Saccharomyces cerevisiae. Nat Methods 2008;5:239
741.
[78] Simmer F, Tijsterman M, Parrish S, Koushika SP, Nonet ML,
Fire A, et al. Loss of the putative RNA-directed RNA polymerase
RRF-3 makes C. elegans hypersensitive to RNAi. Curr Biol
2002;12:1317 e 9.
[79] Lehner B, Calixto A, Crombie C, Tischler J, Fortunato A,
Chalfie M, et al. Loss of LIN-35, the Caenorhabditis elegans
ortholog of the tumor suppressor p105Rb, results in enhanced
RNA interference. Genome Biol 2006;7:R4.
[80] Calixto A, Chelur D, Topalidou I, Chen X, Chalfie M. Enhanced
neuronal RNAi
e
41.
[61] Sopko R, Huang D, Preston N, Chua G, Papp B, Kafadar K, et al.
Mapping pathways and phenotypes by systematic gene over-
expression. Mol Cell 2006;21:319 e 30.
[62] Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC.
Potent and specific genetic interference by double-stranded RNA
in Caenorhabditis elegans. Nature 1998;391:806 e 11.
[63] Fraser AG, Kamath RS, Zipperlen P, Martinez-Campos M,
Sohrmann M, Ahringer J. Functional genomic analysis of C.
elegans chromosome I by systematic RNA interference. Nature
2000;408:325 e 30.
[64] Gonczy P, Echeverri C, Oegema K, Coulson A, Jones SJ,
Copley RR, et al. Functional genomic analysis of cell division in
C. elegans using RNAi of genes on chromosome III. Nature
2000;408:331 e 6.
[65] Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS,
Ahringer J, et al. Genome-wide RNAi analysis of Caenorhabditis
elegans fat regulatory genes. Nature 2003;421:268 e 72.
[66] Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M,
et al. Systematic functional analysis of the Caenorhabditis ele-
gans genome using RNAi. Nature 2003;421:231 e 7.
[67] Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. A
systematic RNAi screen identifies a critical role for mitochondria
in C. elegans longevity. Nat Genet 2003;33:40
e
in C. elegans using SID-1. Nat Methods
2010;7:554 e 9.
[81] Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K,
Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA
interference in cultured mammalian cells. Nature 2001;411:
494 e 8.
[82] Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, et al.
Genes and mechanisms related to RNA interference regulate
expression of the small temporal RNAs that control C. elegans
developmental timing. Cell 2001;106:23 e 34.
[83] Ketting RF, Fischer SE, Bernstein E, Sijen T, Hannon GJ,
Plasterk RH. Dicer functions in RNA interference and in synthesis
of small RNA involved in developmental timing in C. elegans.
Genes Dev 2001;15:2654 e 9.
[84] Knight SW, Bass BL. A role for the RNase III enzyme DCR-1 in
RNA interference and germ line development in Caenorhabditis
elegans. Science 2001;293:2269
8.
[68] Pothof J, van Haaften G, Thijssen K, Kamath RS, Fraser AG,
Ahringer J, et al. Identification of genes that protect the C. elegans
genome against mutations by genome-wide RNAi. Genes Dev
2003;17:443 e 8.
[69] Simmer F, Moorman C, van der Linden AM, Kuijk E, van den
Berghe PV, Kamath RS, et al. Genome-wide RNAi of C. elegans
using the hypersensitive rrf-3 strain reveals novel gene functions.
PLoS Biol 2003;1:E12.
e
71.
[85] Moerman DG, Barstead RJ. Towards a mutation in every gene in
Caenorhabditis elegans. Briefings Funct Genomics Proteomics
2008;7:195 e 204.
[86] Flibotte S, Edgley ML, Maydan J, Taylor J, Zapf R, Waterston R,
et al. Rapid high resolution single nucleotide polymorphism-
comparative genome hybridization mapping in Caenorhabditis
elegans. Genetics 2009;181:33 e 7.
e
Search WWH ::




Custom Search