Biology Reference
In-Depth Information
BOX 6.1 Synthetic Genetic Array (SGA)
e Continued
Double mutant plate
Digital
camera
Microscope
Image acquisition
Image acquisition
Colony size quantification
Quantification of cell parameters
Smaller
Average
Larger
Correction for systematic effects
Model training and binary classification
Smaller
Average
Control
Mutants
Larger
ε = ab−a × b
Measurement of genetic interactions
Network construction
 
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