Effectors of Rab GTPases: Rab Binding Specificity and Their Role in Coordination of Rab Function and Localization - Ras Superfamily Small G Proteins: Biology and Mechanisms 2 - page 47

Rab8a:OCRL1 Rab11a:MyoVb

Rab27a:Slp2-a Rab7a:RILP

Rab3a:Rabphilin-3a Rab27b:Slac2-a

conserved

hydrophobic charged neutral

variable

Fig. 3.4 Conservation of Rab:effector interaction sites. Ribbon representation of Rab proteins
taken from the Rab:effector structures summarized in Table 3.1 . In comparison to Fig. 3.1 , the Rab
proteins and their effectors have been rotated by 90 in opposite directions to allow a visualization
of the binding sites. All Rab residues containing atoms that are within 5 Å of an effector atom are