Biomedical Engineering Reference
In-Depth Information
Figure 7. Preformed tumor size changes of the recipients transplanted with empty and CYP2B1 cell-
enclosing microcapsules. The nude mice each were used as recipients of empty and cell-enclosing
microcapsules. Tumor size just before capsule implantation was set to 1 and each block represents the
proportional size of the original tumor (Reproduced with permission, from Sakai S et al. Mol. Cancer
Ther. [48] @ 2005 American Association for Cancer Research).
Figure 8. Time-course of diffusion of bovine serum albumin from 10 mL Krebs Ringer Hepes buffer
solution (pH 7.4) into 5 mL of microcapsules at 37°C. C
0
, C
L
: initial concentration and concentration of
bovine serum albumin at each time point. (■): Non-treated alginate-agarose microcapsules, (●):
Alginate-agarose microcapsules soaked in 0.05 wt% chitosan-acetic acid aqueous solution (pH 6.3) for
10 min (Reproduced with permission, from Sakai S et al. Biochem. Eng. J. [38] @ 2006 Elsevier).
