Biomedical Engineering Reference
In-Depth Information
6. Conclusion
The foregoing review has demonstrated the eco-friendly and biocompatible biopolymer
poly(γ-glutamic acid) can be a potential material for flocculating turbid waters, and
scavenging cationic dyes and chemical mutagens. Various physical and chemical factors
affecting the flocculation as well as adsorption of cationic dyes and chemical mutagens were
elaborated. Though the synthetic alternatives may be effective and inexpensive, their
application could be restricted from the environmental and health point of view. On the
contrary, biopolymers are generally non-toxic and biodegradable, but the major pitfall
limiting the practical application is their high cost. Nevertheless, the commercial viability
may be enhanced by synthesizing extracellular biopolymers through large-scale fermentation
by employing simple and cost-effective downstream processing methods. Future research on
these topics should focus on a more realistic system involving column operations for cationic
dye removal and in vivo study for scavenging chemical mutagens.
References
[1] Ivánovics, G.; Bruckner, V. Z. Immunitatsforsch. 1937, 90, 304-318.
[2] Ivánovics, G.; Erdös, L. Z. Immunitatsforsch. 1937, 90, 5-19.
[3] Fujii, H. Nippon Nogeikagaku Kaishi , 1963, 37, 407-411.
[4] Fujii, H. Nippon Nogeikagaku Kaishi , 1963, 37, 474.
[5] Shih, I. L.; Van, Y. T. Bioresour. Technol. 2001, 79, 207-225
[6] Bovarnick, M. J. Biol. Chem. 1942, 145, 415-424.
[7] Ward, R. M.; Anderson, R. F.; Dean, F. K. Biotechnol. Bioeng. 1963, 5, 41-48.
[8] Troy, F. A. J. Biol. Chem . 1973, 248, 305-316.
[9] Murao, S. Koubunshi 1969, 16, 1204-1212.
[10] Thorne, C. B.; Gómez, C. G.; Blind, G. R.; Housewright, R. D. J. Bacteriol. 1953, 65,
472-478.
[11] Thorne, C. B.; Gómez, C. G.; Noyes, H. E. Housewright, R. D. J. Bacteriol. 1954, 68,
307-315.
[12] Housewright, R. D. In The Bacteria: A Treatise on Structure and Function ; Gunsalus,
I. C.; Stanier, R. Y.; Eds.; Academic Press: New York, 1962; pp 389-412.
[13] Nitccki, D. E.; Goodman, J. W. In Chemistry and Biochemistry of Amino Acids,
Peptides and Proteins ; Weinstein, B.; Ed.; Marcel Dekker: New York, 1971, pp 87-92.
[14] Sung, M. H. ; Park, C.; Kim, C. J.; Poo, H.; Soda, K.; Ashiuchi, M. Chemical Record
2005, 5, 352-366.
[15] Ho, G. H.; Ho, T. I.; Hsieh, K. H.; Su, Y. C.; Lin, P. Y.; Yang, J.; Yang, K. H.; Yang,
S. C. J. Chin. Chem. Soc . 2006, 53, 1363-1384.
[16] Xu, H.; Jiang, M.; Li, H.; Lu, D.; Quyang, P. Process Biochem. 2005, 40, 519-523.
[17] Shih, I. L.; Van, Y. T.; Shen, M. H. Mini-Rev. Med. Chem . 2004, 4, 179.
[18] Matsusaki, M.; Serizawa, T.; Kishida, A.; Endo, T.; Akashi, M. Bioconjugate Chem .
2002, 13, 23.
[19] Mark, S. S.; Crusberg, T. C.; DaCunha, C. M.; Di Iorio, A. A. Biotechnol. Prog . 2006,
22, 523.
[20] Radu, J. E. F.; Novak, I.; Hartmann, J. F.; Borbely, J. Polym. Prep . 2006, 47, 420.
Search WWH ::




Custom Search