Support for Cooperative Experiments in e-Science: From Scientific Work flows to Knowledge Sharing - Identification of Ligand Binding Site and Protein-Protein Interaction Area - page 132

Chapter 7
Support for Cooperative Experiments
in e-Science: From Scientific Workflows
to Knowledge Sharing

Adam S. Z. Belloum , Reginald Cushing, Spiros Koulouzis,
Vladimir Korkhov, Dmitry Vasunin, Victor Guevara-Masis,
Zhiming Zhao, and Marian Bubak

Keywords e-Science ￿ Work fl ow ￿ Storage resources ￿ Uniform interface
￿ Geographically distributed computing resources ￿ Knowledge sharing ￿ Virtual
organization ￿ Material analysis of complex surface ￿ Preprocessing phase
￿ Experimentation process ￿ Hyper-spectral data cube ￿ Multivariate data analysis
￿ Integrated application ￿ Life-cycle ￿ Searching work fl ows ￿ Reproducibility of
results ￿ Interoperability between different work fl ows ￿ Dissemination ￿ Work fl ow
support ￿ Virtual data system ￿ Shared repository ￿ Process flow template ￿ Executable
operations ￿ Pegasus ￿ Proxy-service ￿ Single nucleotide polymorphism ￿ Individual
therapy

7.1 Introduction

The term e-Science describes computational and data-intensive science. It has
become a complementary experiment paradigm alongside the traditional in vivo and
in vitro experiment paradigms. e-Science opens new doors for scientists and with it,

A. S. Z. Belloum ( * ) ￿ R. Cushing ￿ S. Koulouzis ￿ V. Guevara-Masis ￿ Z. Zhao
The Informatics Institute , University of Amsterdam , Amsterdam , The Netherlands
e-mail: [e-mail] ; [e-mail] ; [e-mail] ; [e-mail]
V. Korkhov ￿ D. Vasunin
Faculty of Applied Math and Control Processes, St. Petersburg
State University , Saint Petersburg , Russia
e-mail: [e-mail] ; [e-mail]
M. Bubak
AGH University of Science and Technology Krakow, Poland and the Informatics Institute,
University of Amsterdam , Amsterdam , The Netherlands
e-mail: [e-mail]; [e-mail]