Biomedical Engineering Reference
In-Depth Information
Ta b l e 1
Maximum elastic
modulus (mean
T
(days)
E
max
,
1
(MPa)
E
max
,
6
(MPa)
stdev) of
the electro-spun scaffold at
the first loading (
E
max
,
1
)and
sixth loading (
E
max
,
6
)priorto
degradation (
T
=
0 days) and
after different times of
degradation (
T
=
5to34
days)
±
0
.
99
±
0
.
16
1
.
14
±
0
.
23
0
±
±
5
1
.
29
0
.
35
1
.
64
0
.
56
10
1
.
23
±
0
.
16
1
.
54
±
0
.
17
14
0
.
98
±
0
.
09
1
.
21
±
0
.
20
18
0
.
99
±
0
.
12
1
.
19
±
0
.
13
22
1
.
03
±
0
.
14
1
.
30
±
0
.
05
26
0
.
99
±
0
.
34
1
.
15
±
0
.
41
30
0
.
95
±
0
.
20
0
.
82
±
0
.
13
34
0
.
76
±
0
.
10
0
.
43
±
0
.
26
Overall
1
.
02
±
0
.
24
1
.
17
±
0
.
42
3 Constitutive Modeling of Degradation-Induced Changes
in Scaffold Mechanics
The tensile test data were handled in Scilab (The Scilab Consortium, Domaine de
Voluceau, France). Force values were filtered with a seven element triangular win-
dow moving average filter in order to remove test associated noise. Test sample
dimensions and force-displacement data of strain
ε
0 to 20 % of the final exten-
sion were extracted from the Instron data files. From this force-displacement dataset,
each sample was represented during characterisation by 11 points at equal spacing.
=
Fig. 8
SEM micrographs of electro-spun scaffold samples showing section of fibres after 14 days
(a) and 34 days (b) of degradation before mechanical testing, and after degradation for 5 days (c, d)
and 26 days (e, f) and subsequent mechanical testing to failure (The magnification and scale bar
length are:
a
:
×
7500, 1 µm;
b
:
×
7500, 1 µm;
c
:
×
50, 500 µm;
d
:
×
2000, 10 µm;
e
:
×
15, 1 mm;
f
:
×
2000, 10 µm)
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