Chemistry Reference
In-Depth Information
Oral zinc induces the metallothionein synthesis in
the enterocytes. This mechanism is used therapeutically
to reduce copper uptake in Wilson's disease.
Metallothionein will complex copper in these cells that
subsequently will be shed off into the feces (Barceloux,
1999; Danks, 1991; Lönnerdal, 1996; Roberts and
Schilsky, 2003).
Liver transplantation must be considered in
decompensated liver disease (Roberts and Schilsky,
2003).
Allergic contact dermatitis caused by copper has
been treated successfully with hydrocortisone ointment
and with the removal of the offending agent (Saltzer
and Wilson, 1968).
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