Biology Reference
In-Depth Information
a
d
H
3
C
O
N
H
2
N
d
a
N
NH
N
N
N
-
O
a
T
A
d
a
NH
2
O
N
d
N
N
HN
a
N
N
d
O
a
H
2
N
C
G
FIGURE 5.2
Representative structures for canonical Watson
Crick base pairs.
e
RB69 DNA polymerase
“Classical DNA polymerase”
Pol
η
“Non-classical DNA polymerase”
Duplex
DNA
Duplex
DNA
Fingers
Thumb
Thumb
Fingers
Palm
Palm
FIGURE 5.3
X-ray crystallographic structures of high-fidelity replicative DNA polymerase (left panel) and low-fidelity "specialized" DNA
polymerase (right panel).
