Biology Reference
In-Depth Information
etoposide-induced DNA double-strand breaks via topoisomerase
II. Cancer Res 2007;67(15):7078 e 81.
251. Issaeva N, Thomas HD, Djureinovic T, et al. 6-thioguanine
selectively kills BRCA2-defective tumors and overcomes PARP
inhibitor resistance. Cancer Res 2010;70(15):6268 e 76.
252. Roos WP, Nikolova T, Quiros S, et al. Brca2/Xrcc2 dependent
HR, but not NHEJ, is required for protection against O(6)-
methylguanine triggered apoptosis, DSBs and chromosomal
aberrations by a process leading to SCEs. DNA Repair (Amst)
2009;8(1):72 e 86.
253. Kennedy RD, Quinn JE, Mullan PB, Johnston PG, Harkin DP. The
role of BRCA1 in the cellular response to chemotherapy. J Natl
Cancer Inst 2004;96(22):1659 e 68.
254. Byrski T, Huzarski T, Dent R, et al. Response to neoadjuvant
therapy with cisplatin in BRCA1-positive breast cancer patients.
Breast Cancer Res Treat 2009;115(2):359 e 63.
255. Byrski T, Gronwald J, Huzarski T, et al. Pathologic complete
response rates in young women with BRCA1-positive breast
cancers after neoadjuvant chemotherapy. J Clin Oncol 2010;28(3):
375 e 9.
256. Carey LA. Targeted chemotherapy? Platinum in BRCA1-
dysfunctional breast cancer. J Clin Oncol 2010;28(3):361 e 3.
257. Kriege M, Seynaeve C, Meijers-Heijboer H, et al. Sensitivity to
first-line chemotherapy for metastatic breast cancer in BRCA1
and BRCA2 mutation carriers. J Clin Oncol 2009;27(23):3764 e 71.
258. Bast Jr RC, Mills GB. Personalizing therapy for ovarian cancer:
BRCAness and beyond. J Clin Oncol 2010;28(22):3545 e 8.
259. Held KD, Willers H. Molecular and cellular basis of radiation
injury. In: Shrieve DC, Loeffler JS, editors. Human Radiation Injury .
Philadelphia: Lippincott Williams & Wilkins; 2011. p. 1 e 13.
260. Willers H, Held KD. Introduction to clinical radiation biology.
Hematol Oncol Clin North Am 2006;20(1):1 e 24.
261. Ward JF. DNA damage produced by ionizing radiation in
mammalian cells: identities, mechanisms of formation, and rep-
arability. Prog Nucleic Acid Res Mol Biol 1988;35:95 e 125.
262. Radford IR. The level of induced DNA double-strand breakage
correlates with cell killing after X-irradiation. Int J Radiat Biol
Relat Stud Phys Chem Med 1985;48(1):45 e 54.
263. Dahm-Daphi J, Dikomey E, Pyttlik C. Relationship between non-
reparable DNA strand breaks and cell survival studied in
X-irradiated CHO, CHO K1, xrs1 and xrs5 cells. Int J Radiat Biol
1994;65(6):657 e 63.
264. Goodhead DT. Initial events in the cellular effects of ionizing
radiations: clustered damage in DNA. Int J Radiat Biol 1994;65(1):
7 e 17.
265. Lomax ME, Cunniffe S, O'Neill P. 8-OxoG retards the activity of
the ligase III/XRCC1 complex during the repair of a single-strand
break, when present within a clustered DNA damage site. DNA
Repair (Amst) 2004;3(3):289 e 99.
266. Georgakilas AG, Bennett PV, Wilson 3rd DM, Sutherland BM.
Processing of bistranded abasic DNA clusters in gamma-
irradiated human hematopoietic cells. Nucleic Acids Res 2004;
32(18):5609 e 20.
267. Eot-Houllier G, Eon-Marchais S, Gasparutto D, Sage E. Process-
ing of a complex multiply damaged DNA site by human cell
extracts and purified repair proteins. Nucleic Acids Res 2005;33(1):
260 e 71.
268. Henner WD, Rodriguez LO, Hecht SM, Haseltine WA. Gamma
ray induced deoxyribonucleic acid strand breaks. 3' Glycolate
termini. J Biol Chem 1983;258(2):711 e 3.
269. Dahm-Daphi J, Hubbe P, Horvath F, et al. Nonhomologous end-
joining of site-specific but not of radiation-induced DNA double-
strand breaks is reduced in the presence of wild-type p53.
Oncogene 2005;24(10):1663 e 72.
270. Sutherland BM, Bennett PV, Sutherland JC, Laval J. Clustered
DNA damages induced by x rays in human cells. Radiat Res 2002;
157(6):611 e 6.
271. Gulston M, Fulford J, Jenner T, de Lara C, O'Neill P. Clustered
DNA damage induced by gamma radiation in human fibroblasts
(HF19), hamster (V79-4) cells and plasmid DNA is revealed as
Fpg and Nth sensitive sites. Nucleic Acids Res 2002;30(15):
3464 e 72.
272. Hinz JM, Yamada NA, Salazar EP, Tebbs RS, Thompson LH.
Influence of double-strand-break repair pathways on radiosen-
sitivity throughout the cell cycle in CHO cells. DNA Repair (Amst)
2005;4(7):782 e 92.
273. Takata M, Sasaki MS, Sonoda E, et al. Homologous recombination
and non-homologous end-joining pathways of DNA double-
strand break repair have overlapping roles in the maintenance of
chromosomal integrity in vertebrate cells. EMBO J 1998;17(18):
5497 e 508.
274. Rothkamm K, Kruger I, Thompson LH, Lobrich M. Pathways of
DNA double-strand break repair during the mammalian cell
cycle. Mol Cell Biol 2003;23(16):5706 e 15.
275. Shibata A, Conrad S, Birraux J, et al. Factors determining DNA
double-strand break repair pathway choice in G2 phase. EMBO J
2011.
276. Lee SE, Mitchell RA, Cheng A, Hendrickson EA. Evidence for
DNA-PK-dependent and -independent DNA double-strand
break repair pathways in mammalian cells as a function of the
cell cycle. Mol Cell Biol 1997;17(3):1425 e 33.
277. Tamulevicius P, Wang M, Iliakis G. Homology-directed repair is
required for the development of radioresistance during S phase:
interplay between double-strand break repair and checkpoint
response. Radiat Res 2007;167(1):1 e 11.
278. Richardson C, Moynahan ME, Jasin M. Double-strand break
repair by interchromosomal recombination: suppression of
chromosomal translocations. Genes Dev 1998;12(24):3831 e 42.
279. Johnson RD, Jasin M. Sister chromatid gene conversion is
a prominent double-strand break repair pathway in mammalian
cells. EMBO J 2000;19(13):3398 e 407.
280. Xia F, Taghian DG, DeFrank JS, et al. Deficiency of human BRCA2
leads to impaired homologous recombination but maintains
normal nonhomologous end joining. Proc Natl Acad Sci USA 2001;
98(15):8644 e 9.
281. Scully R, Ganesan S, Vlasakova K, Chen J, Socolovsky M,
Livingston DM. Genetic analysis of BRCA1 function in a defined
tumor cell line. Molecular Cell 1999;4:1093 e 9.
282. Zhang J, Willers H, Feng Z, et al. Chk2 phosphorylation of
BRCA1 regulates DNA double-strand break repair. Mol Cell Biol
2004;24(2):708 e 18.
283. Alpert TE, Haffty BG. Conservative management of breast cancer
in BRCA1/2 mutation carriers. Clin Breast Cancer 2004;5(1):37 e 42.
284. Gluckman E. Radiosensitivity in Fanconi anemia: application to
the conditioning for bone marrow transplantation. Radiother
Oncol 1990;18. Suppl. 1:88 e 93.
285. Hows JM, Chapple M, Marsh JC, et al. Bone marrow trans-
plantation for Fanconi's anaemia: the Hammersmith experience
1977-89. Bone Marrow Transplant 1989;4(6):629 e 34.
286. Alter BP. Radiosensitivity in Fanconi's anemia patients. Radiother
Oncol 2002;62(3):345 e 7.
287. Marcou Y, D'Andrea A, Jeggo PA, Plowman PN. Normal cellular
radiosensitivity in an adult Fanconi anaemia patient with marked
clinical radiosensitivity. Radiother Oncol 2001;60(1):75 e 9.
288. Bremer M, Schindler D, Gross M, Dork T, Morlot S, Karstens JH.
Fanconi's anemia and clinical radiosensitivity report on two adult
patients with locally advanced solid tumors treated by radio-
therapy. Strahlenther Onkol 2003;179(11):748 e 53.
Search WWH ::




Custom Search