Biology Reference
In-Depth Information
FIGURE 8.1. A schematic representation of the middle and outer ear showing the
structures affected by mutations in various genes. The structures altered by the
mutation are indicated in black. These alterations include duplications, hypomor-
phisms, or missing elements. The reported genes represent homozygous null mutants
unless otherwise stated. eam = external auditory meatus, i = incus, m = malleus,
ow = oval window, s = stapes, st = stapedius muscle, tm = tympanic membrane, tr =
tympanic ring, tt = tensor tympani muscle. [Reprinted from Trends in Neuroscience
Vol. 22, Fekete, DM, Development of the vertebrate ear: insights from knockouts
and mutants, pp. 263-269, Copyright 1999, with permission from Elsevier Science.]
